Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12072841 | 0.86 | HTR2C (0.53) | HTR2CHTR2BNAMPTL3MBTL1 | |
| SCHEMBL1668564 | 0.81 | KDM4A (0.41) | NAMPT | |
| SCHEMBL20808158 | 0.80 | L3MBTL1 (0.46) | HTR2CNAMPTL3MBTL1 | |
| SCHEMBL617292 | 0.79 | NAMPT (0.49) | HTR2CHTR2BNAMPTL3MBTL1 | |
| SCHEMBL10278112 | 0.79 | NAMPT (0.47) | HTR2CHTR2BNAMPTL3MBTL1 | |
| SCHEMBL19641909 | 0.78 | ROCK2 (0.49) | JAK3HTR2CNAMPTL3MBTL1 | |
| SCHEMBL3180689 | 0.77 | L3MBTL1 (0.61) | NAMPTL3MBTL1 | |
| SCHEMBL10233162 | 0.76 | NAMPT (0.47) | HTR2CHTR2BNAMPTL3MBTL1 | |
| SCHEMBL23960541 | 0.75 | NAMPT (0.44) | JAK3NAMPTL3MBTL1 | |
| SCHEMBL252733 | 0.74 | NAMPT (0.45) | HTR2CHTR2BNAMPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771345-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2017-09-26 | — | — | US | disclosed |
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295874-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, HCCS | JAK3 3780/4885HTR2C 4174/4885HTR2B 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.