Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928220 | 0.86 | CDK5 (0.48) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL12055622 | 0.85 | LMNA (0.43) | SMN1; SMN2POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL2605500 | 0.85 | PKM (0.49) | POLBALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8350324 | 0.85 | PKM (0.49) | POLBALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL8351735 | 0.85 | PKM (0.49) | POLBALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL1934310 | 0.84 | CA1 (0.48) | ALDH1A1KMT2AGLANAAAMEN1 | |
| SCHEMBL8707251 | 0.83 | GAA (0.49) | GAANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL8707255 | 0.83 | GAA (0.49) | GAANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL18855407 | 0.82 | GAA (0.44) | GAARAB9ASMN1; SMN2MAPTNAAA | |
| SCHEMBL12032617 | 0.82 | GAA (0.44) | GAARAB9ASMN1; SMN2MAPTNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |