Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981184 | 0.84 | ALDH1A1 (0.55) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL1668771 | 0.84 | TSHR (0.47) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL27995557 | 0.76 | TSHR (0.52) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL6500392 | 0.73 | TSHR (0.52) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL28022638 | 0.73 | TSHR (0.52) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL19712775 | 0.72 | ORAI1 (0.41) | KMT2ACES2CES1CA5A | |
| SCHEMBL1668721 | 0.71 | HSPB1 (0.51) | LMNAALDH1A1TDP1MAPTGAA | |
| SCHEMBL13857813 | 0.71 | TP53 (0.50) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL29758194 | 0.70 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL127723 | 0.70 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |