Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758194 | 0.87 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL127723 | 0.87 | TSHR (0.61) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL28382242 | 0.85 | TSHR (0.59) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL1668772 | 0.84 | TSHR (0.40) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL6981176 | 0.81 | ALDH1A1 (0.66) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| Phosphoric Acid SCHEMBL28445592 | 0.81 | TSHR (0.53) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| Cadaverine Tartrate SCHEMBL28355308 | 0.79 | TP53 (0.49) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL29953015 | 0.76 | TSHR (0.52) | TSHRLMNAALDH1A1TDP1ALOX15 | |
| SCHEMBL128893 | 0.76 | ENPP2 (0.46) | TSHRALDH1A1CES2CES1CA2 | |
| SCHEMBL6701294 | 0.75 | TSHR (0.46) | TSHRLMNAALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012154213-A1 | COFLUORONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2012-11-15 | — | — | WO | disclosed |
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |