Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668823 | 0.88 | TPSAB1 (0.48) | KMT2ATSHRPARP14 | |
| SCHEMBL13967564 | 0.88 | KMT2A (0.52) | KMT2ATSHRDRD2NPC1 | |
| SCHEMBL1668585 | 0.88 | KMT2A (0.44) | KMT2ATSHRDRD2 | |
| SCHEMBL14879836 | 0.81 | MGLL (0.51) | KMT2APARP14 | |
| SCHEMBL1668837 | 0.81 | MGLL (0.56) | — | |
| SCHEMBL1668846 | 0.80 | PARP14 (0.46) | KMT2ATSHRPARP14NPC1 | |
| SCHEMBL1668899 | 0.78 | EGLN1 (0.46) | PARP14 | |
| SCHEMBL14898131 | 0.77 | KMT2A (0.44) | KMT2ATSHRDRD2 | |
| SCHEMBL1668865 | 0.76 | TPSAB1 (0.51) | KMT2ATSHRPARP14 | |
| SCHEMBL14879880 | 0.76 | KMT2A (0.41) | KMT2ATSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2485678-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | disclosed |