Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MGAM | O43451 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | SI | P14410 | 6/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 9/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688486 | 0.85 | MGAM (0.59) | RAB9ASMN1; SMN2ALDH1A1HPGDMGAM | |
| SCHEMBL16688479 | 0.84 | CSNK2A2 (0.72) | RAB9ASMN1; SMN2ALDH1A1HPGDMGAM | |
| SCHEMBL16688499 | 0.82 | RAB9A (0.64) | RAB9ASMN1; SMN2ALDH1A1MGAMGAA | |
| SCHEMBL330586 | 0.76 | KCNMA1 (0.71) | RAB9ASMN1; SMN2ALDH1A1HPGDMGAM | |
| SCHEMBL6240008 | 0.75 | PIM1 (0.70) | RAB9ASMN1; SMN2ALDH1A1GAANPC1 | |
| SCHEMBL16688492 | 0.75 | RAB9A (0.76) | RAB9ASMN1; SMN2ALDH1A1HPGDMGAM | |
| SCHEMBL15116284 | 0.71 | AVPR2 (0.67) | SMN1; SMN2ALDH1A1HPGDKMT2APOLB | |
| SCHEMBL29176359 | 0.71 | RAB9A (0.60) | RAB9ASMN1; SMN2ALDH1A1HPGDMGAM | |
| SCHEMBL16688458 | 0.71 | RAB9A (0.61) | RAB9ASMN1; SMN2ALDH1A1HPGDMGAM | |
| SCHEMBL1067010 | 0.69 | HDAC2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126507-A1 | COMPOUNDS TO TREAT HEARING LOSS | US ARMY, SECRETARY OF THE ARMY | 2015-05-07 | — | — | US | disclosed |
| US-20150126507-A1 | COMPOUNDS TO TREAT HEARING LOSS | US ARMY, SECRETARY OF THE ARMY | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126507-A1 | COMPOUNDS TO TREAT HEARING LOSS | NGF, DCX, OTC | RAB9A 4077/4885SMN1; SMN2 2048/4885ALDH1A1 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.