Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | SI | P14410 | 2/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688482 | 0.85 | RAB9A (0.60) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL16688499 | 0.85 | RAB9A (0.64) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL16688479 | 0.84 | CSNK2A2 (0.72) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL6238132 | 0.75 | TAS1R3 (0.68) | GAARAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL16073054 | 0.74 | NPC1 (0.69) | GAARAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL26267624 | 0.73 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16688458 | 0.73 | RAB9A (0.61) | MGAMGAASIMGAM2CSNK2A2 | |
| SCHEMBL3223685 | 0.73 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL12121115 | 0.72 | NPC1 (0.62) | GAARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8555330 | 0.71 | TP53 (0.70) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126507-A1 | COMPOUNDS TO TREAT HEARING LOSS | US ARMY, SECRETARY OF THE ARMY | 2015-05-07 | — | — | US | disclosed |
| US-20150126507-A1 | COMPOUNDS TO TREAT HEARING LOSS | US ARMY, SECRETARY OF THE ARMY | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126507-A1 | COMPOUNDS TO TREAT HEARING LOSS | NGF, DCX, OTC | MGAM 4835/4885GAA 3997/4885SI 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.