Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.65 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.63 |
| ▸ | HPGD | P15428 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288556 | 0.85 | MAPT (0.69) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL16689174 | 0.84 | ALDH1A1 (0.71) | MAPTNPSR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2649274 | 0.80 | GCGR (0.76) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL2647850 | 0.80 | GCGR (1.00) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL2648864 | 0.79 | GCGR (0.74) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL2647883 | 0.78 | GCGR (0.73) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL3282241 | 0.78 | MAPT (0.71) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL15281386 | 0.78 | ALDH1A1 (1.00) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL2649360 | 0.78 | GCGR (0.72) | GCGRMAPTNPSR1SAE1UBA2 | |
| SCHEMBL2648262 | 0.78 | GCGR (0.72) | GCGRMAPTNPSR1SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305899-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | HUTCHINSON FRED CANCER RES (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170305899-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | HUTCHINSON FRED CANCER RES (US) | 2017-10-26 | — | — | US | disclosed |
| US-20150126519-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-05-07 | — | — | US | disclosed |
| US-20150126519-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305899-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | BLM, DNA2, DCLRE1B | GCGR 4615/4885MAPT 3731/4885NPSR1 4878/4885 |
| US-20150126519-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | BLM, DNA2, DCLRE1B | GCGR 4615/4885MAPT 3731/4885NPSR1 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.