Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.71 |
| ▸ | RAB9A | P51151 | 8/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689136 | 0.84 | GCGR (0.66) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15281386 | 0.83 | ALDH1A1 (1.00) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15426134 | 0.82 | ALDH1A1 (0.69) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15281367 | 0.82 | ALDH1A1 (0.98) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL3923750 | 0.78 | ALDH1A1 (0.71) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5804275 | 0.77 | ALDH1A1 (0.69) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15281366 | 0.77 | RORC (0.64) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL15281362 | 0.76 | KMT2A (0.71) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL2650404 | 0.75 | GCGR (0.72) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5804059 | 0.74 | ALDH1A1 (0.69) | ALDH1A1RAB9AMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305899-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | HUTCHINSON FRED CANCER RES (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170305899-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | HUTCHINSON FRED CANCER RES (US) | 2017-10-26 | — | — | US | disclosed |
| US-20150126519-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-05-07 | — | — | US | disclosed |
| US-20150126519-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305899-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | BLM, DNA2, DCLRE1B | ALDH1A1 2061/4885RAB9A 2030/4885MAPT 3731/4885 |
| US-20150126519-A1 | ANTIBIOTIC COMPOUNDS AND COMPOSITIONS, AND METHODS FOR IDENTIFICATION THEREOF | BLM, DNA2, DCLRE1B | ALDH1A1 2061/4885RAB9A 2030/4885MAPT 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.