Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25964498 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL14393166 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AKISS1R | |
| SCHEMBL23616214 | 0.84 | TGFBR1 (0.32) | TSHRTGFBR1 | |
| SCHEMBL25771654 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MEN1LMNAKMT2AKISS1R | |
| SCHEMBL14771687 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL17629512 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL20210924 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1LMNAKMT2ATSHR | |
| SCHEMBL24870953 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1LMNAKMT2AMAPT | |
| SCHEMBL18973380 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1LMNAKMT2AKISS1R | |
| SCHEMBL12214818 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1LMNAKMT2AKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215016-A1 | SYNTHESIS OF PEPTIDE EPOXY KETONES | SANDOZ GMBH (AT) | 2016-07-28 | — | — | US | disclosed |
| US-9187442-B2 | Method for producing stereoselective epoxyketone compound | NISSAN CHEMICAL INDUSTIES, LTD. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150126755-A1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126755-A1 | METHOD FOR PRODUCING STEREOSELECTIVE EPOXYKETONE COMPOUND | HSD17B7, CYP51A1, AKR1B10 | ALDH1A1 331/4885MEN1 2492/4885LMNA 3031/4885 |
| US-20160215016-A1 | SYNTHESIS OF PEPTIDE EPOXY KETONES | VIP, PTMS, EPOR | ALDH1A1 3590/4885MEN1 1897/4885LMNA 2576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.