SCHEMBL1669191

SCHEMBL1669191

CC(=O)c1csc(C(C)=O)n1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.49
ALDH1A1 P00352 3/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 3/20 0.41
PLA2G4A P47712 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
ADORA2A P29274 1/20 0.36
ADORA1 P30542 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
FPR3 P25089 1/20 0.34
FPR2 P25090 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16369857 0.87 KDM1A (0.47) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL1808582 0.87 L3MBTL1 (0.55) KDM1AALDH1A1PLA2G4AL3MBTL1
SCHEMBL25446547 0.85 ALDH1A1 (0.39) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL15652132 0.85 HTR2B (0.45) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL24130265 0.85 ALDH1A1 (0.39) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL4683786 0.85 KDM1A (0.46) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL15933940 0.82 MAPT (0.51) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL16371343 0.82 MAPT (0.45) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL25446548 0.82 PLA2G4A (0.46) KDM1AALDH1A1NPC1RAB9AMAPT
SCHEMBL17716403 0.82 KDM1A (0.41) KDM1AALDH1A1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2808736-B1 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2018-07-18 EP claimed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP claimed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP claimed
CN-218608963-U Constant temperature agitating unit convenient to equipment 滕州市悟通香料有限责任公司 2023-03-14 CN disclosed
EP-2808736-B1 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2018-07-18 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
CN-101088046-B Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO 2011-05-25 CN disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
CN-101088046-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-12-12 CN disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed
EP-0545085-B1 Process for obtaining 2-acetyl-1-pyrroline in encapsulated form, intermediates and final product NESTLE SA (CH) 2000-03-01 EP disclosed
EP-0535713-B1 Use of carbomethoxy-2-pyrroline-1 NESTLE SA (CH) 1995-04-19 EP disclosed
EP-0545085-A1 Process for obtaining 2-acetyl-1-pyrroline in encapsulated form, intermediates and final product SOCIETE DES PRODUITS NESTLE S.A. (CH) 1993-06-09 EP disclosed
EP-0535713-A1 Use of carbomethoxy-2-pyrroline-1 SOCIETE DES PRODUITS NESTLE S.A. (CH) 1993-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R KDM1A 13/4885ALDH1A1 1170/4885NPC1 3988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.