Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16691340 | 0.88 | GRM5 (0.41) | GRM5MAPTCYP2D6 | |
| SCHEMBL16692858 | 0.78 | CYP2C9 (0.43) | MAPTCYP2D6CLPP | |
| SCHEMBL16692848 | 0.78 | PKM (0.39) | GRM5MAPT | |
| SCHEMBL16692850 | 0.78 | CYP2A13 (0.43) | MAPTCYP1A2CYP2D6CLPP | |
| SCHEMBL16692866 | 0.76 | TNIK (0.44) | MAPTCYP1A2 | |
| SCHEMBL30443099 | 0.76 | TNIK (0.44) | MAPTCYP1A2 | |
| SCHEMBL16691273 | 0.75 | PSEN1 (0.53) | GRM5MAPTCYP1A2 | |
| SCHEMBL16692874 | 0.74 | ROCK2 (0.50) | — | |
| SCHEMBL16691284 | 0.74 | PSEN1 (0.45) | GRM5MAPT | |
| SCHEMBL16692826 | 0.73 | TNIK (0.46) | CLPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066697-A1 | FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF | FORUM PHARMACEUTICALS INC. (US) | 2015-05-07 | — | — | WO | disclosed |