Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE8A | O60658 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | PDE8B | O95263 | 1/20 | 0.40 |
| ▸ | PDE6A | P16499 | 1/20 | 0.40 |
| ▸ | PDE6G | P18545 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13130996 | 0.80 | DAO (0.46) | KDM4DPARP1PDE2APDE6DPDE8A | |
| SCHEMBL19134467 | 0.79 | PARP1 (0.50) | KDM4DPARP1CYP1A2 | |
| SCHEMBL29792892 | 0.77 | PARP1 (0.56) | PARP1HPGDCYP1A2CYP2C9 | |
| SCHEMBL527381 | 0.77 | PARP1 (0.56) | PARP1HPGDCYP1A2CYP2C9 | |
| SCHEMBL16695720 | 0.76 | PARP1 (0.63) | KDM4DLDHAPARP1AURKAHPGD | |
| SCHEMBL11603501 | 0.74 | FEN1 (0.54) | PARP1AURKACYP1A2CYP2C19MAPT | |
| SCHEMBL23500591 | 0.73 | KDM4D (0.47) | KDM4DLDHAPARP1AURKAHPGD | |
| SCHEMBL31330116 | 0.73 | PARP1 (0.46) | KDM4DLDHAPARP1AURKAHPGD | |
| SCHEMBL31330201 | 0.73 | PARP1 (0.46) | KDM4DLDHAPARP1AURKAHPGD | |
| SCHEMBL23509253 | 0.72 | MAT2A (0.38) | PDE9AHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115225-A1 | PYRAZOLE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2021-06-17 | — | — | WO | disclosed |
| US-9708332-B2 | Respiratory syncytial virus inhibitors | MEDIVIR AB (SE) | 2017-07-18 | — | — | US | disclosed |
| US-9708332-B2 | Respiratory syncytial virus inhibitors | MEDIVIR AB (SE) | 2017-07-18 | — | — | US | disclosed |
| US-20160272646-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2016-09-22 | — | — | US | disclosed |
| WO-2015065338-A1 | QUINAZOLINE BASED RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272646-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | HIF1AN, RNASEH1, RTF1 | KDM4D 3912/4885LDHA 2461/4885PARP1 2944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.