Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.50 |
| ▸ | FLT3 | P36888 | 3/20 | 0.50 |
| ▸ | JAK2 | O60674 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | CSF1R | P07333 | 2/20 | 0.50 |
| ▸ | CLK2 | P49760 | 2/20 | 0.50 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169043 | 0.84 | METAP2 (0.50) | PIM1FLT3JAK2CHEK1PRKD3 | |
| SCHEMBL29440610 | 0.73 | MAOA (0.61) | PIM1FLT3JAK2CHEK1PRKD3 | |
| SCHEMBL389647 | 0.73 | MAOA (0.61) | PIM1FLT3JAK2CHEK1PRKD3 | |
| SCHEMBL24716430 | 0.70 | — | — | |
| SCHEMBL158747 | 0.70 | F2 (0.52) | LMNAHPGDALDH1A1MAPTHSD17B10 | |
| SCHEMBL29440558 | 0.70 | F2 (0.52) | LMNAHPGDALDH1A1MAPTHSD17B10 | |
| SCHEMBL30933343 | 0.68 | HSD17B10 (0.59) | PIM1FLT3JAK2CHEK1PRKD3 | |
| Methane SCHEMBL29008285 | 0.68 | F2 (0.50) | LMNAHPGDALDH1A1MAPTHSD17B10 | |
| SCHEMBL14543828 | 0.68 | HSD17B10 (0.59) | PIM1FLT3JAK2CHEK1PRKD3 | |
| SCHEMBL26124848 | 0.68 | DAO (0.53) | PIM1FLT3JAK2CHEK1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065338-A1 | QUINAZOLINE BASED RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |