Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.61 |
| ▸ | MAOB | P27338 | 10/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | CFD | P00746 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440610 | 1.00 | MAOA (0.61) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL2382755 | 0.85 | F2 (0.56) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL30549739 | 0.85 | F2 (0.56) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL694149 | 0.78 | MAOA (0.61) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL14448380 | 0.78 | F2 (0.56) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL1147630 | 0.78 | F2 (0.56) | MAOAMAOBF2CFDACHE | |
| SCHEMBL62706 | 0.78 | LMNA (0.58) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL1668291 | 0.78 | F2 (0.56) | MAOAMAOBF2CFDGSK3A | |
| SCHEMBL3132671 | 0.78 | MAOA (0.57) | MAOAMAOBF2CFDLMNA | |
| SCHEMBL31460362 | 0.78 | MAOA (0.57) | MAOAMAOBF2CFDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 701 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118727475-B | Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers | 绍兴劲草化工有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-118910629-A | Electrochemical synthesis method of quinazolinone derivative | 齐齐哈尔医学院 | 2024-11-08 | — | — | CN | claimed |
| CN-118727475-A | Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers | 绍兴劲草化工有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-117603144-A | Synthesis method of polysubstituted quinazolinone | 常熟泓德生物科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-110437233-B | Tryptanthrin derivative containing olefine acid and preparation method and application thereof | 同济大学 | 2022-01-07 | — | — | CN | claimed |
| CN-110283192-B | Preparation method and application of tryptanthrin derivative containing boric acid | 同济大学 | 2021-08-06 | — | — | CN | claimed |
| CN-110372611-B | Method for selectively synthesizing polysubstituted dihydro quinazolinone or quinazolinone | 常熟理工学院 | 2021-05-04 | — | — | CN | claimed |
| US-9974992-B2 | Fire extinguishing composition comprising carboxylic acid derivative | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-05-22 | — | — | US | claimed |
| EP-3095488-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING CARBOXYLIC ACID DERIVATIVE | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | claimed |
| US-20160332015-A1 | Fire Extinguishing Composition Comprising Carboxylic Acid Derivative | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| US-4728673-A | BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-01 | — | — | US | claimed |
| US-12622909-B2 | Allosteric EGFR inhibitors and methods of use thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2026-05-12 | — | — | US | disclosed |
| EP-4730479-A2 | FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME | Kyoto University (JP) | 2026-04-22 | — | — | EP | disclosed |
| EP-4727923-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | University of Georgia Research Foundation, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260098012-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | UNIV GEORGIA (US) | 2026-04-09 | — | — | US | disclosed |
| US-4346034-A | Process for preparing imidazodiazepines | HOFFMANN-LA ROCHE INC. (US) | 1982-08-24 | — | — | US | disclosed |
| US-4346032-A | ANTIDOTES TO OVERDOSES OF BENZODIAZEPINE TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1982-08-24 | — | — | US | disclosed |
| US-4346035-A | Process for preparing imidazodiazepines | HOFFMANN-LA ROCHE INC. (US) | 1982-08-24 | — | — | US | disclosed |
| US-4316839-A | Imidazodiazepine derivatives | HOFFMAN-LA ROCHE INC. (US) | 1982-02-23 | — | — | US | disclosed |
| EP-0027214-A1 | Imidazodiazepine derivatives, process and intermediates for their preparation, medicaments containing them and their therapeutic application | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622909-B2 | Allosteric EGFR inhibitors and methods of use thereof | EGFR, ERBB3, ERBB2 | MAOA 3384/4885MAOB 3189/4885F2 4852/4885 |
| US-20260098012-A1 | TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA | CD47, SLC11A2, G6PD | MAOA 4393/4885MAOB 4337/4885F2 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.