Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16695822 | 0.76 | PIM1 (0.50) | KDM4EALDH1A1LMNAHPGDCDK5 | |
| SCHEMBL29891935 | 0.73 | MAOA (0.61) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL694149 | 0.73 | MAOA (0.61) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL29440558 | 0.70 | F2 (0.52) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL158747 | 0.70 | F2 (0.52) | KDM4EALDH1A1GLAGAAHTT | |
| Methane SCHEMBL29008285 | 0.68 | F2 (0.50) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL482202 | 0.68 | DAO (0.53) | DAO | |
| SCHEMBL30716975 | 0.68 | DAO (0.53) | DAO | |
| SCHEMBL4950054 | 0.67 | DAO (0.70) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL15379639 | 0.66 | ACHE (0.67) | KDM4EALDH1A1GLAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065338-A1 | QUINAZOLINE BASED RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |