SCHEMBL694149

SCHEMBL694149

O=c1[nH]c2ccc(F)cc2c(=O)o1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 9/20 0.61
MAOB P27338 9/20 0.61
ACHE P22303 2/20 0.61
F2 P00734 1/20 0.56
CFD P00746 1/20 0.56
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 2/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
HTT P42858 1/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
FEN1 P39748 1/20 0.47
CDK5 Q00535 1/20 0.47
CDK5R1 Q15078 1/20 0.47
LMNA P02545 1/20 0.45
HPGD P15428 1/20 0.45
MPO P05164 1/20 0.45
AR P10275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29891935 1.00 MAOA (0.61) MAOAMAOBACHEF2CFD
SCHEMBL1202554 0.85 F2 (0.56) MAOAMAOBACHEF2CFD
SCHEMBL30639060 0.85 F2 (0.56) MAOAMAOBACHEF2CFD
SCHEMBL9272079 0.82 MAOA (0.55) MAOAMAOBACHEF2CFD
SCHEMBL62706 0.78 LMNA (0.58) MAOAMAOBACHEF2CFD
SCHEMBL1147630 0.78 F2 (0.56) MAOAMAOBACHEF2CFD
SCHEMBL3132671 0.78 MAOA (0.57) MAOAMAOBACHEF2CFD
SCHEMBL1668291 0.78 F2 (0.56) MAOAMAOBACHEF2CFD
SCHEMBL31460362 0.78 MAOA (0.57) MAOAMAOBACHEF2CFD
SCHEMBL1202291 0.78 NOS1 (0.62) MAOAMAOBACHEF2CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118727475-B Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2025-04-29 CN claimed
CN-118727475-A Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2024-10-01 CN claimed
CN-117603144-A Synthesis method of polysubstituted quinazolinone 常熟泓德生物科技有限公司 2024-02-27 CN claimed
CN-116417566-A Positive electrode plate, preparation method thereof and lithium ion battery 蜂巢能源科技(无锡)有限公司 2023-07-11 CN claimed
CN-116283803-A Preparation method of flumazenil intermediate 上海旭东海普药业有限公司 2023-06-23 CN claimed
CN-114976249-A Electrolyte and sodium ion battery 湖南钠方新能源科技有限责任公司 2022-08-30 CN claimed
CN-110372611-B Method for selectively synthesizing polysubstituted dihydro quinazolinone or quinazolinone 常熟理工学院 2021-05-04 CN claimed
EP-4730479-A2 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME Kyoto University (JP) 2026-04-22 EP disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
US-20250246685-A1 FLAME-RETARDANT NON-AQUEOUS ELECTROLYTIC SOLUTION AND SECONDARY BATTERY USING SAME KYOTO UNIVERSITY (JP) 2025-07-31 US disclosed
US-20250213700-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY FOX CHASE CHEMICAL DIVERSITY CENTER, INC. 2025-07-03 US disclosed
WO-2025120994-A1 SECONDARY BATTERY NON-AQUEOUS ELECTROLYTE AND SECONDARY BATTERY PROVIDED WITH SAME ステラケミファ株式会社 2025-06-12 WO disclosed
CN-118727475-B Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2025-04-29 CN disclosed
US-4346032-A ANTIDOTES TO OVERDOSES OF BENZODIAZEPINE TRANQUILIZERS HOFFMANN-LA ROCHE INC. (US) 1982-08-24 US disclosed
US-4346034-A Process for preparing imidazodiazepines HOFFMANN-LA ROCHE INC. (US) 1982-08-24 US disclosed
US-4346036-A ALKYLATION; AMIDATION; TRANQUILIZER ANTAGONIST HOFFMANN-LA ROCHE INC. (US) 1982-08-24 US disclosed
US-4316839-A Imidazodiazepine derivatives HOFFMAN-LA ROCHE INC. (US) 1982-02-23 US disclosed
EP-0027214-A1 Imidazodiazepine derivatives, process and intermediates for their preparation, medicaments containing them and their therapeutic application F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-04-22 EP disclosed
US-4261997-A 4-Alkyl-pyrazolo[5,1-b]-quinazolin-9(4H)-ones and anti-allergic compositions containing them WARNER-LAMBERT COMPANY (US) 1981-04-14 US disclosed
EP-0015065-A1 Pyrazolo (5,1-b) quinazolin-9(4H)-one derivatives, process for their preparation and pharmaceutical compositions containing them WARNER-LAMBERT COMPANY (US) 1980-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA MAOA 4125/4885MAOB 3702/4885ACHE 1829/4885
US-20250213700-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CELL-SPECIFIC PHARMACOLOGY DDT, ABCG2, CES2 MAOA 242/4885MAOB 182/4885ACHE 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.