Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.53 |
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478883 | 0.92 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL29522725 | 0.92 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL31510405 | 0.84 | HPGD (0.50) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL13387474 | 0.80 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL5339818 | 0.80 | NOTUM (0.57) | RAB9ANPC1SMN1; SMN2HPGDNOTUM | |
| SCHEMBL31036105 | 0.79 | NOTUM (0.61) | RAB9ANPC1SMN1; SMN2HPGDNOTUM | |
| SCHEMBL29522898 | 0.79 | ALDH1A1 (0.50) | RAB9ANPC1HPGDCYP1A2CYP2C9 | |
| SCHEMBL28490404 | 0.79 | ALDH1A1 (0.50) | RAB9ANPC1HPGDCYP1A2CYP2C9 | |
| SCHEMBL16406932 | 0.78 | NOTUM (0.54) | RAB9ANPC1HPGDNOTUMALDH1A1 | |
| SCHEMBL16686040 | 0.76 | NPC1 (0.63) | RAB9ANPC1HPGDCYP1A2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066413-A1 | OXAZOLIDINONE HYDROXAMIC ACID COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-05-07 | — | — | WO | disclosed |