Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720540 | 0.81 | HTT (0.54) | KMT2ARAB9AHTTPKMGPR55 | |
| SCHEMBL442779 | 0.75 | MCL1 (0.60) | KMT2ARAB9AHTTLMNAMAPK1 | |
| SCHEMBL443475 | 0.74 | KDM4E (0.73) | KMT2ARAB9AHTTGPR55LMNA | |
| SCHEMBL879305 | 0.74 | KCNH2 (0.59) | KMT2ARAB9AHTTGPR55LMNA | |
| Hydrochloric Acid SCHEMBL9789912 | 0.74 | MCL1 (0.58) | KMT2ARAB9AHTTLMNAMAPK1 | |
| SCHEMBL15619119 | 0.72 | KCNH2 (0.56) | KMT2ARAB9AHTTLMNAMAPK1 | |
| SCHEMBL114250 | 0.72 | KMT2A (0.60) | KMT2ARAB9AHTTLMNAMAPK1 | |
| SCHEMBL28810376 | 0.71 | KCNH2 (0.63) | KMT2ARAB9AHTTPKMLMNA | |
| SCHEMBL30608270 | 0.71 | NPC1 (0.66) | KMT2ARAB9AHTTLMNAMAPK1 | |
| SCHEMBL25472764 | 0.71 | KCNH2 (0.58) | KMT2ARAB9AHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2017-06-29 | — | — | US | disclosed |
| US-9532983-B2 | Benzofuran compounds, compositions, kits and/or methods thereof | SAVANNAH STATE UNIVERSITY (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | KMT2A 1248/4885RAB9A 4758/4885ADRA2A 78/4885 |
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | KMT2A 1248/4885RAB9A 4758/4885ADRA2A 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.