Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.68 |
| ▸ | MMP2 | P08253 | 4/20 | 0.61 |
| ▸ | MMP13 | P45452 | 4/20 | 0.61 |
| ▸ | NMT2 | O60551 | 1/20 | 0.55 |
| ▸ | NMT1 | P30419 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735539 | 0.89 | EDNRA (0.53) | EDNRAMMP2MMP13NMT2NMT1 | |
| SCHEMBL10737734 | 0.87 | NPC1 (0.60) | EDNRAMMP2MMP13NMT2NMT1 | |
| SCHEMBL16698582 | 0.85 | NPC1 (0.53) | EDNRAMMP2MMP13TP53MAPT | |
| SCHEMBL20305366 | 0.83 | EDNRA (0.71) | EDNRAMMP2MMP13NMT2NMT1 | |
| SCHEMBL10736988 | 0.82 | MMP2 (0.59) | MMP2MMP13TP53MAPTTSHR | |
| SCHEMBL3616780 | 0.82 | EDNRA (1.00) | EDNRAMMP2MMP13TP53MAPT | |
| SCHEMBL16697971 | 0.81 | KMT2A (0.59) | TP53MAPTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5866924 | 0.77 | LMNA (0.79) | TP53MAPTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3616553 | 0.77 | MMP2 (1.00) | MMP2MMP13 | |
| SCHEMBL3616557 | 0.77 | MMP2 (1.00) | MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2017-06-29 | — | — | US | disclosed |
| US-9532983-B2 | Benzofuran compounds, compositions, kits and/or methods thereof | SAVANNAH STATE UNIVERSITY (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | EDNRA 1392/4885MMP2 4444/4885MMP13 4088/4885 |
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | EDNRA 1392/4885MMP2 4444/4885MMP13 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.