SCHEMBL16700402

SCHEMBL16700402

Nc1ccc(CN(Cc2ccc(N)cc2)Cc2ccc(N)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.61
▸ ALDH1A1 P00352 4/20 0.55
▸ CYP3A4 P08684 4/20 0.55
▸ TDP1 Q9NUW8 3/20 0.55
▸ GFER P55789 2/20 0.55
▸ TSHR P16473 2/20 0.55
▸ LOXL2 Q9Y4K0 1/20 0.52
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ MAOB P27338 4/20 0.46
▸ MAOA P21397 2/20 0.46
▸ HRH3 Q9Y5N1 2/20 0.44
▸ TP53 P04637 1/20 0.40
▸ CNR2 P34972 1/20 0.40
▸ CYP19A1 P11511 2/20 0.39
▸ RECQL P46063 2/20 0.39
▸ PSMD14 O00487 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ CYP17A1 P05093 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3156612 0.90 MAOB (0.62) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL15391387 0.90 MAOB (0.62) MAPTALDH1A1CYP3A4TDP1GFER
Hydrochloric Acid SCHEMBL16699788 0.88 MAOB (0.64) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL16706883 0.88 ACHE (0.59) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL1813157 0.85 HRH3 (0.67) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL1956276 0.85 MAPT (0.64) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL9125321 0.83 MAPT (0.62) MAPTALDH1A1CYP3A4TDP1GFER
Hydrochloric Acid SCHEMBL4461628 0.83 HRH3 (0.64) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL3152392 0.81 MAPT (0.60) MAPTALDH1A1CYP3A4TDP1GFER
SCHEMBL1206593 0.81 MAPT (0.78) MAPTALDH1A1CYP3A4TDP1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092157-A1 MACROPOROUS-STRUCTURED POLYMER AEROGELS BLUESHIFT MAT INC (US) 2026-04-02 — — US disclosed
US-12516172-B2 Macroporous-structured polymer aerogels Blueshift Materials, Inc. (US) 2026-01-06 — — US disclosed
EP-4655158-A2 FLAME AND THERMAL BARRIER MATERIALS Blueshift Materials, Inc. (US) 2025-12-03 — — EP disclosed
US-20250353984-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2025-11-20 — — US disclosed
US-20250346018-A1 LOW-DIELECTRIC CONSTANT, LOW-DISSIPATION FACTOR LAMINATES INCLUDING AEROGEL LAYERS BLUESHIFT MAT INC (US) 2025-11-13 — — US disclosed
US-12448492-B2 Organic polymer aerogels comprising microstructures Blueshift Materials, Inc. (US) 2025-10-21 — — US disclosed
US-12404382-B2 Highly branched non-crosslinked aerogel, methods of making, and uses thereof Blueshift Materials, Inc. (US) 2025-09-02 — — US disclosed
US-12391024-B2 Low-dielectric constant, low-dissipation factor laminates including aerogel layers Blueshift Materials, Inc. (US) 2025-08-19 — — US disclosed
US-20250197583-A1 THERMALLY TREATED POLYAMIC AMIDE AEROGEL Blueshift Materials, Inc. (US) 2025-06-19 — — US disclosed
US-20250162282-A1 FLAME AND THERMAL BARRIER MATERIALS Blueshift Materials, Inc. (US) 2025-05-22 — — US disclosed
US-20170121483-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF Blueshift Materials, Inc. 2017-05-04 — — US disclosed
WO-2017074751-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT INTERNATIONAL MATERIALS, INC. (US) 2017-05-04 — — WO disclosed
US-9585880-B2 Cyclic amino compounds for use in the treatment of cardiac disorders UNIVERSITETET I OSLO (NO) 2017-03-07 — — US disclosed
US-9556111-B2 Tertiary amines for use in the treatment of cardiac disorders UNIVERSITETET I OSLO (NO) 2017-01-31 — — US disclosed
US-9556111-B2 Tertiary amines for use in the treatment of cardiac disorders UNIVERSITETET I OSLO (NO) 2017-01-31 — — US disclosed
US-9556111-B2 Tertiary amines for use in the treatment of cardiac disorders UNIVERSITETET I OSLO (NO) 2017-01-31 — — US disclosed
US-20150141456-A1 CYCLIC AMINO COMPOUNDS FOR USE IN THE TREATMENT OF CARDIAC DISORDERS UNIVERSITETET I OSLO (NO) 2015-05-21 — — US disclosed
US-20150133510-A1 TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS UNIVERSITETET I OSLO (NO) 2015-05-14 — — US disclosed
US-20150133510-A1 TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS UNIVERSITETET I OSLO (NO) 2015-05-14 — — US disclosed
US-20150133510-A1 TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS UNIVERSITETET I OSLO (NO) 2015-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092157-A1 MACROPOROUS-STRUCTURED POLYMER AEROGELS ACR, AQP4, AQP3 MAPT 132/4885ALDH1A1 3320/4885CYP3A4 1739/4885
US-20150133510-A1 TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS TNNI3, TNNT2, MYLK2 MAPT 1886/4885ALDH1A1 1191/4885CYP3A4 4312/4885
US-20150141456-A1 CYCLIC AMINO COMPOUNDS FOR USE IN THE TREATMENT OF CARDIAC DISORDERS TNNI3, TNNT2, AKAP8L MAPT 2915/4885ALDH1A1 2654/4885CYP3A4 4621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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