Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.62 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670086 | 1.00 | SLC5A1 (0.62) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL9486948 | 0.88 | SLC5A1 (0.63) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL8518437 | 0.86 | SLC5A1 (0.58) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL14675184 | 0.85 | SLC5A1 (0.49) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL14675183 | 0.85 | SLC5A1 (0.49) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL11484354 | 0.85 | SLC5A1 (0.60) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL11484358 | 0.85 | SLC5A1 (0.60) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL10848226 | 0.85 | TBXAS1 (0.49) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL10848229 | 0.85 | TBXAS1 (0.49) | SLC5A1SLC5A2NPC1TP53RAB9A | |
| SCHEMBL4064477 | 0.84 | ALDH1A1 (0.56) | SLC5A1SLC5A2THRBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066696-A | Optical alignment composition, alignment layer formed using the same and LCD having the alignment layer | SAMSUNG DISPLAY DEVICES CO. LTD. (KR) | 2000-05-23 | — | — | US | claimed |
| US-12435067-B2 | Truncated itraconazole analogues and methods of use thereof | UNIVERSITY OF CONNECTICUT (US) | 2025-10-07 | — | — | US | disclosed |
| US-11999119-B2 | Method for manufacturing polarizing plate | LG CHEM, LTD. (KR) | 2024-06-04 | — | — | US | disclosed |
| EP-2956437-B1 | ALBICIDIN DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS | UNIV BERLIN TECH (DE) | 2023-05-10 | — | — | EP | disclosed |
| WO-2023000398-A1 | LYCORINE β-ARYL ACRYLATE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东达因海洋生物制药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| US-20220324849-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | UNIVERSITY OF CONNECTICUT | 2022-10-13 | — | — | US | disclosed |
| CN-113416199-B | Lycorine beta-aryl acrylate derivative and preparation method and application thereof | 山东达因海洋生物制药股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-20210252813-A1 | METHOD FOR MANUFACTURING POLARIZING PLATE | LG CHEM, LTD. (KR) | 2021-08-19 | — | — | US | disclosed |
| WO-2021030174-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2021-02-18 | — | — | WO | disclosed |
| US-10308595-B2 | Albicidin derivatives, their use and synthesis | Technische Universität Berlin (DE) | 2019-06-04 | — | — | US | disclosed |
| US-5976640-A | Optical alignment composition, alignment layer formed using the same and LCD having the alignment layer | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1999-11-02 | — | — | US | disclosed |
| US-5946064-A | Alignment layer, method for forming alignment layer and LCD having the same | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1999-08-31 | — | — | US | disclosed |
| US-5925423-A | Optical alignment polymer, alignment layer formed using the same and liquid crystal display device having the alignment layer | SAMSUNG DISPLAY DEVICES CO., LTD (KR) | 1999-07-20 | — | — | US | disclosed |
| EP-0887666-A2 | Passive polarisation modulating optical element and method of making such an element | Sharp Kabushiki Kaisha (JP) | 1998-12-30 | — | — | EP | disclosed |
| EP-0887692-A2 | Method of making a spatial light modulation | Sharp Kabushiki Kaisha (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5824377-A | POLYSILOXANE HAVING PENDANT CINNAMOYL GROUP | LG ELECTRONICS INC. (KR) | 1998-10-20 | — | — | US | disclosed |
| EP-0829744-A2 | Parallax barrier and display passive polarisation modulating optical element & method of making such an element | SHARP KABUSHIKI KAISHA (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5538823-A | Liquid crystal device utilizing thermostable polymeric material | GOLDSTAR CO., LTD. (KR) | 1996-07-23 | — | — | US | disclosed |
| US-4189484-A | Antihypertensive quinazoline derivatives | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-19 | — | — | US | disclosed |
| US-4026896-A | ANTIALLERGENS | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) | 1977-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308595-B2 | Albicidin derivatives, their use and synthesis | MB, ALB, BCAT2 | SLC5A1 2465/4885SLC5A2 2720/4885NPC1 4471/4885 |
| US-12435067-B2 | Truncated itraconazole analogues and methods of use thereof | GLI1, SHH, SMO | SLC5A1 4407/4885SLC5A2 4603/4885NPC1 2100/4885 |
| US-20220324849-A1 | TRUNCATED ITRACONAZOLE ANALOGUES AND METHODS OF USE THEREOF | GLI1, SHH, SMO | SLC5A1 4407/4885SLC5A2 4603/4885NPC1 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.