Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338819 | 0.88 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1THRBATMTBXAS1 | |
| SCHEMBL7338829 | 0.88 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1THRBATMTBXAS1 | |
| SCHEMBL11686354 | 0.87 | THRB (0.65) | THRBATMTBXAS1POLBHCAR2 | |
| SCHEMBL11684594 | 0.85 | THRB (0.62) | THRBATMTBXAS1POLBHCAR2 | |
| SCHEMBL38652226 | 0.85 | ABCG2 (0.63) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1670086 | 0.84 | SLC5A1 (0.62) | ALDH1A1THRBATMTBXAS1HCAR2 | |
| SCHEMBL1670087 | 0.84 | SLC5A1 (0.62) | ALDH1A1THRBATMTBXAS1HCAR2 | |
| SCHEMBL2449264 | 0.83 | POLB (0.53) | ALDH1A1L3MBTL1THRBATMTBXAS1 | |
| SCHEMBL2449262 | 0.83 | POLB (0.53) | ALDH1A1L3MBTL1THRBATMTBXAS1 | |
| SCHEMBL10848226 | 0.82 | TBXAS1 (0.49) | ALDH1A1L3MBTL1THRBATMTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | claimed |
| US-20050186141-A1 | Transdermal aerosol compositions | ACRUX DDS PTY LTD. | 2005-08-25 | — | — | US | claimed |
| EP-1534241-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | Acrux DDS Pty Ltd (AU) | 2005-06-01 | — | — | EP | claimed |
| EP-1534214-A1 | TOPICAL COSMETIC COMPOSITIONS | Cosmeceutic Solutions Pty Ltd (AU) | 2005-06-01 | — | — | EP | claimed |
| WO-2004000275-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | ACRUX DDS PTY LTD (AU) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | claimed |
| US-20090098069-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | DRUGTECH CORPORATION (US) | 2009-04-16 | — | — | US | disclosed |
| WO-2009036311-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | DRUGTECH CORPORATION (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20050271692-A1 | Topical cosmetic compositions | COSMECEUTIC SOLUTIONS PTY. LTD. | 2005-12-08 | — | — | US | disclosed |
| US-20050186141-A1 | Transdermal aerosol compositions | ACRUX DDS PTY LTD. | 2005-08-25 | — | — | US | disclosed |
| EP-1534241-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | Acrux DDS Pty Ltd (AU) | 2005-06-01 | — | — | EP | disclosed |
| EP-1534214-A1 | TOPICAL COSMETIC COMPOSITIONS | Cosmeceutic Solutions Pty Ltd (AU) | 2005-06-01 | — | — | EP | disclosed |
| US-20050002868-A1 | Method of treatment of a female suffering from androgen insufficiency | ACRUX DDS PTY LTD. | 2005-01-06 | — | — | US | disclosed |
| WO-2004000242-A1 | TOPICAL COSMETIC COMPOSITIONS | COSMECEUTIC SOLUTIONS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
| WO-2004000275-A1 | TRANSDERMAL AEROSOL COMPOSITIONS | ACRUX DDS PTY LTD (AU) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050271692-A1 | Topical cosmetic compositions | CUTA, MITF, DSG1 | ALDH1A1 1409/4885L3MBTL1 4672/4885THRB 3697/4885 |
| US-20050186141-A1 | Transdermal aerosol compositions | TSLP, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TRPA1 | ALDH1A1 1538/4885L3MBTL1 4804/4885THRB 2966/4885 |
| US-20090098069-A1 | TRANSDERMAL, ALCOHOL-FREE, PHARMACEUTICAL COMPOSITIONS | NOTUM, TSLP, FAR1 | ALDH1A1 532/4885L3MBTL1 3414/4885THRB 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.