Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND2 | P30279 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888711 | 0.96 | CHRNA7 (0.43) | GAAALOX15CHRNA7MEN1KMT2A | |
| SCHEMBL6888597 | 0.84 | CHRNA7 (0.45) | CHRNA7CHRNA1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6887263 | 0.83 | CHRNA7 (0.43) | GAAALOX15CHRNA7MEN1KMT2A | |
| SCHEMBL6888190 | 0.82 | CHRNA7 (0.47) | GAAALOX15CHRNA7MEN1KMT2A | |
| SCHEMBL1668992 | 0.81 | ALDH1A1 (0.38) | GAAALOX15CHRNA7MEN1KMT2A | |
| SCHEMBL6888927 | 0.79 | KDM4E (0.43) | GAAALOX15CHRNA7MEN1KMT2A | |
| SCHEMBL6888541 | 0.79 | CHRNA7 (0.46) | GAAALOX15CHRNA7CHRNA1CHRNB2 | |
| SCHEMBL6886841 | 0.79 | CHRNA7 (0.45) | GAAALOX15CHRNA7KMT2ACHRNA1 | |
| SCHEMBL1670209 | 0.79 | ADRA1A (0.42) | GAAALOX15CHRNA7MEN1KMT2A | |
| SCHEMBL6889887 | 0.78 | CHRNA7 (0.40) | CHRNA7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488520-A1 | CONDENSED AZINE - DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE ACETYLCHOLINE RECEPTOR | MSD Oss B.V. (NL) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045258-A1 | CONDENSED AZINE - DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE ACETYLCHOLINE RECEPTOR | N.V. ORGANON (NL) | 2011-04-21 | — | — | WO | disclosed |