Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806795 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL7461538 | 0.81 | USP2 (0.55) | LMNAUSP2APP | |
| SCHEMBL16560335 | 0.80 | LMNA (0.46) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL2772686 | 0.79 | TDP1 (0.39) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL1646775 | 0.77 | LMNA (0.44) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL8762763 | 0.77 | USP2 (0.44) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL35977 | 0.76 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL27395790 | 0.76 | LMNA (0.48) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL8520334 | 0.75 | USP2 (0.61) | LMNAL3MBTL1TDP1USP2SPHK1 | |
| SCHEMBL515147 | 0.75 | USP2 (0.52) | LMNAUSP2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102647978-A | Pharmaceutical composition comprising poorly soluble active ingredient and hyperbranched polymer | LEK PHARMACEUTICALS | 2012-08-22 | — | — | CN | disclosed |
| EP-2485716-A2 | PHARMACEUTICAL COMPOSITION COMPRISING POORLY SOLUBLE ACTIVE INGREDIENT AND HYPERBRANCHED POLYMER | LEK Pharmaceuticals d.d. (SI) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042463-A2 | PHARMACEUTICAL COMPOSITION COMPRISING POORLY SOLUBLE ACTIVE INGREDIENT AND HYPERBRANCHED POLYMER | LEK PHARMACEUTICALS D.D. (SI) | 2011-04-14 | — | — | WO | disclosed |