Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619757 | 0.78 | LMNA (0.65) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL2955749 | 0.78 | LMNA (0.65) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL3909140 | 0.78 | LMNA (0.65) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL1670192 | 0.77 | LMNA (0.37) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL21806795 | 0.77 | LMNA (0.37) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL3227829 | 0.75 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL1403818 | 0.75 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| SCHEMBL3009609 | 0.75 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Mannitol SCHEMBL20572201 | 0.75 | LMNA (0.69) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Mannitol SCHEMBL3887158 | 0.75 | LMNA (0.69) | LMNAL3MBTL1TDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10899750-B2 | Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity | ANGION BIOMEDICA CORP. (US) | 2021-01-26 | — | — | US | disclosed |
| US-20180009793-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP (US) | 2018-01-11 | — | — | US | disclosed |
| US-20140256727-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2014-09-11 | — | — | US | disclosed |
| US-8772326-B2 | Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity | Anigion Biomedica Corp. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20110184038-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2011-07-28 | — | — | US | disclosed |
| EP-2313093-A2 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | Angion Biomedica CORP. (US) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010005580-A2 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184038-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, HGFAC | LMNA 2470/4885L3MBTL1 1960/4885TDP1 4563/4885 |
| US-20140256727-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, HGFAC | LMNA 2470/4885L3MBTL1 1960/4885TDP1 4563/4885 |
| US-10899750-B2 | Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity | HGF, HDGF, HGFAC | LMNA 2697/4885L3MBTL1 2052/4885TDP1 4477/4885 |
| US-20180009793-A1 | METHODS AND COMPOSITIONS OF SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, HGFAC | LMNA 2470/4885L3MBTL1 1960/4885TDP1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.