SCHEMBL2772686

SCHEMBL2772686

O=S(=O)(O)CCCCOC(O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM4E B2RXH2 2/20 0.32
PDE4A P27815 1/20 0.32
APP P05067 1/20 0.31
USP2 O75604 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21806795 0.79 LMNA (0.37) TDP1LMNAL3MBTL1PDE4AAPP
SCHEMBL1670192 0.79 LMNA (0.37) TDP1LMNAL3MBTL1PDE4AAPP
SCHEMBL4621765 0.75 USP2 (0.44) TDP1LMNAL3MBTL1KDM4EUSP2
SCHEMBL5573408 0.73 TDP1 (0.55) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL28278210 0.73 TDP1 (0.55) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL28256211 0.70 TDP1 (0.50) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL252338 0.70 TDP1 (0.50) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL5683104 0.68 TDP1 (0.48) TDP1LMNAL3MBTL1KDM4EPDE4A
Mannitol SCHEMBL28766951 0.67 LMNA (0.61) TDP1LMNAL3MBTL1KDM4EPDE4A
SCHEMBL8641932 0.67 TDP1 (0.52) TDP1LMNAL3MBTL1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4327867-A2 PHARMACEUTICAL COMPOSITION COMPRISING GLUCOPYRANOSYL DIPHENYLMETHANE DERIVATIVES, PHARMACEUTICAL DOSAGE FORM THEREOF, PROCESS FOR THEIR PREPARATION AND USES THEREOF FOR IMPROVED GLYCEMIC CONTROL IN A PATIENT Boehringer Ingelheim International GmbH (DE) 2024-02-28 EP disclosed
EP-2395968-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUCOPYRANOSYL DIPHENYLMETHANE DERIVATIVES, PHARMACEUTICAL DOSAGE FORM THEREOF, PROCESS FOR THEIR PREPARATION AND USES THEREOF FOR IMPROVED GLYCEMIC CONTROL IN A PATIENT BOEHRINGER INGELHEIM INT (DE) 2024-01-17 EP disclosed
US-20220211725-A1 Pharmaceutical Composition Comprising Venetoclax ALEMBIC PHARMACEUTICALS LIMITED (IN) 2022-07-07 US disclosed
US-20220193045-A1 PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL DOSAGE FORM, PROCESS FOR THEIR PREPARATION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INT (DE) 2022-06-23 US disclosed
US-20210283156-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INT (DE) 2021-09-16 US disclosed
EP-3854404-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF Boehringer Ingelheim International GmbH (DE) 2021-07-28 EP disclosed
EP-2729151-B1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INT (DE) 2021-03-31 EP disclosed
US-20200268777-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF BOEHRINGER INGELHEIM INT (DE) 2020-08-27 US disclosed
US-20200188337-A1 Pharmaceutical composition and pharmaceutical dosage form comprising (E)-4-(2-(aminomethyl)-3-fluoroallyloxy)-N-tert-butylbenzamide, process for their preparation, methods for treating and uses thereof BOEHRINGER INGELHEIM INT (DE) 2020-06-18 US disclosed
US-10603292-B2 Pharmaceutical composition and pharmaceutical dosage form comprising (E)-4-(2-(aminomethyl)-3-fluoroallyloxy)-N-tert-butylbenzamide, process for their preparation, methods for treating and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2020-03-31 US disclosed
EP-2396005-A1 SGLT-2 INHIBITOR FOR TREATING TYPE 1 DIABETES MELLITUS, TYPE 2 DIABETE MELLITUS, IMPAIRED GLUCOSE TOLERANCE OR HYPERGLYCEMIA Boehringer Ingelheim International GmbH (DE) 2011-12-21 EP disclosed
EP-2252270-A2 FORMULATIONS OF FLIBANSERIN Boehringer Ingelheim International GmbH (DE) 2010-11-24 EP disclosed
WO-2010092123-A1 SGLT-2 INHIBITOR FOR TREATING TYPE 1 DIABETES MELLITUS, TYPE 2 DIABETE MELLITUS, IMPAIRED GLUCOSE TOLERANCE OR HYPERGLYCEMIA BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-08-19 WO disclosed
WO-2010092126-A1 PHARMACEUTICAL COMPOSITION COMPRISING GLUCOPYRANOSYL DIPHENYLMETHANE DERIVATIVES, PHARMACEUTICAL DOSAGE FORM THEREOF, PROCESS FOR THEIR PREPARATION AND USES THEREOF FOR IMPROVED GLYCEMIC CONTROL IN A PATIENT BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-08-19 WO disclosed
WO-2010070023-A2 FORMULATIONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-06-24 WO disclosed
WO-2009100886-A2 FORMULATIONS OF FLIBANSERIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-08-20 WO disclosed
EP-2090297-A1 Formulations of flibanserin Boehringer Ingelheim International GmbH (DE) 2009-08-19 EP disclosed
EP-2054041-A2 FORMULATIONS OF FLIBANSERIN AND METHOD FOR MANUFACTURING THE SAME Boehringer Ingelheim International GmbH (DE) 2009-05-06 EP disclosed
WO-2008019996-A2 FORMULATIONS OF FLIBANSERIN AND METHOD FOR MANUFACTURING THE SAME BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-02-21 WO disclosed
US-20080038347-A1 Extended release tablet formulations of flibanserin and method for manufacturing the same BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200188337-A1 Pharmaceutical composition and pharmaceutical dosage form comprising (E)-4-(2-(aminomethyl)-3-fluoroallyloxy)-N-tert-butylbenzamide, process for their preparation, methods for treating and uses thereof AFF2, FLNB, AFF1 TDP1 1622/4885LMNA 1189/4885L3MBTL1 4793/4885
US-20200268777-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF SLC5A2, SLC5A1, SLC2A2 TDP1 4394/4885LMNA 3438/4885L3MBTL1 4453/4885
US-10603292-B2 Pharmaceutical composition and pharmaceutical dosage form comprising (E)-4-(2-(aminomethyl)-3-fluoroallyloxy)-N-tert-butylbenzamide, process for their preparation, methods for treating and uses thereof AFF2, FLNB, AFF1 TDP1 1622/4885LMNA 1189/4885L3MBTL1 4793/4885
US-20210283156-A1 PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF SLC5A1, SLC5A2, SLC2A1 TDP1 2161/4885LMNA 3460/4885L3MBTL1 4173/4885
US-20220193045-A1 PHARMACEUTICAL COMPOSITION, PHARMACEUTICAL DOSAGE FORM, PROCESS FOR THEIR PREPARATION, METHODS FOR TREATING AND USES THEREOF SLC5A2, SLC5A1, SLC2A2 TDP1 4577/4885LMNA 3484/4885L3MBTL1 4861/4885
US-20220211725-A1 Pharmaceutical Composition Comprising Venetoclax U2AF1, SF3B1, SF3B3 TDP1 151/4885LMNA 1526/4885L3MBTL1 4431/4885
US-20080038347-A1 Extended release tablet formulations of flibanserin and method for manufacturing the same FLNB, FFAR3, FFAR4 TDP1 4139/4885LMNA 781/4885L3MBTL1 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.