Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692593 | 0.89 | DHFR (0.43) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL11980224 | 0.88 | DHFR (0.40) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL13197741 | 0.84 | LMNA (0.54) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL1322385 | 0.83 | DHFR (0.46) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL29423330 | 0.83 | DHFR (0.46) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL12131349 | 0.79 | ALDH1A1 (0.46) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL1323196 | 0.79 | DHFR (0.43) | DHFRPIK3CGLMNAMEN1KMT2A | |
| SCHEMBL24501024 | 0.79 | LMNA (0.50) | LMNAMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL65673 | 0.78 | KMT2A (0.59) | LMNAMEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL7695816 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2ATP53MAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066147-A2 | CONJUGATED POLYMERS | Merck Patent GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067336-A2 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2015-05-14 | — | — | WO | disclosed |