SCHEMBL1322385

SCHEMBL1322385

Brc1ccc(Br)c2nc(-c3ccccc3)c(-c3ccccc3)nc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.46
PIK3CG P48736 1/20 0.46
NQO2 P16083 2/20 0.45
LMNA P02545 5/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
MAPK1 P28482 3/20 0.45
HTT P42858 2/20 0.45
TP53 P04637 2/20 0.45
ADORA2A P29274 1/20 0.43
ADORA1 P30542 1/20 0.43
KDM4E B2RXH2 7/20 0.42
GAA P10253 4/20 0.42
ALDH1A1 P00352 9/20 0.42
HPGD P15428 3/20 0.42
TSHR P16473 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29423330 1.00 DHFR (0.46) DHFRPIK3CGNQO2LMNAMEN1
SCHEMBL12131349 0.96 ALDH1A1 (0.46) DHFRPIK3CGNQO2LMNAMEN1
SCHEMBL14789192 0.88 TDP1 (0.43) DHFRPIK3CGNQO2LMNAMEN1
SCHEMBL16702152 0.83 DHFR (0.47) DHFRPIK3CGLMNAMEN1KMT2A
SCHEMBL13197741 0.82 LMNA (0.54) DHFRPIK3CGLMNAMEN1KMT2A
SCHEMBL20798675 0.81 KMT2A (0.54) DHFRPIK3CGNQO2LMNAMEN1
SCHEMBL30860100 0.81 KMT2A (0.54) DHFRPIK3CGNQO2LMNAMEN1
SCHEMBL20212684 0.80 CKS1B (0.40) DHFRPIK3CGLMNAMEN1KMT2A
SCHEMBL24311024 0.79 KDM4E (0.37) DHFRPIK3CGNQO2LMNAMEN1
SCHEMBL14819242 0.78 ATP4A (0.49) L3MBTL1HTTTP53KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106892908-B Synthetic method of 5- (8-bromo-2, 3-diphenyl quinoxaline-5-yl) thiophene-2-formaldehyde 西安瑞联新材料股份有限公司 2021-04-06 CN claimed
CN-117050324-A Quinoxaline bridged terpyridine iron coordination polymer electrochromic material 南京林业大学 2023-11-14 CN disclosed
CN-101492529-B Soluble polythiophene derivative and application thereof in photoelectric component 财团法人工业技术研究院 2022-10-11 CN disclosed
WO-2022062597-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND USE THEREOF 浙江百可半导体材料有限公司 2022-03-31 WO disclosed
WO-2022062597-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND USE THEREOF 浙江百可半导体材料有限公司 2022-03-31 WO disclosed
CN-112142717-B Thermal activation delayed fluorescent material and application thereof 浙江百可半导体材料有限公司 2022-02-11 CN disclosed
CN-108530423-B Water-soluble aggregation-induced emission quinoxaline compound and preparation method and application thereof 华南理工大学 2021-07-20 CN disclosed
CN-106892908-B Synthetic method of 5- (8-bromo-2, 3-diphenyl quinoxaline-5-yl) thiophene-2-formaldehyde 西安瑞联新材料股份有限公司 2021-04-06 CN disclosed
CN-112142717-A Thermal activation delayed fluorescent material and application thereof 浙江百可半导体材料有限公司 2020-12-29 CN disclosed
EP-3512848-B1 COMPOUNDS WITH CARBAZOLE STRUCTURES MERCK PATENT GMBH (DE) 2020-11-18 EP disclosed
US-20030208032-A1 Fluorene-containing polymers and compounds useful in the preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-11-06 US disclosed
WO-2003020790-A2 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2003-03-13 WO disclosed
US-6514632-B1 Electroluminescent films and coatings for light emitting diodes; efficiency DOW GLOBAL TECHNOLOGIES INC. 2003-02-04 US disclosed
US-6512083-B1 Film prepared from the polymers of this invention. this invention is a light-emitting diode comprised of one or more layers of polymer films, at least one of which is derived from the oligomers and polymers of the invention. DOW GLOBAL TECHNOLOGIES INC. 2003-01-28 US disclosed
US-6362310-B1 LIGHT EMITTING POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-26 US disclosed
US-6353083-B1 CONJUGATED COPOLYMER COMPRISING UNITS DERIVED FROM 9-SUBSTITUTED FLUORENE MONOMERS AND/OR 9,9-DISUBSTITUTED FLUORENE MONOMERS AND TWO DISTINCT RESIDUAL MONOMERIC UNITS THAT HAVE HOLE TRANSPORTING PROPERTIES THE DOW CHEMICAL COMPANY 2002-03-05 US disclosed
EP-1155096-A1 FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM THE DOW CHEMICAL COMPANY (US) 2001-11-21 EP disclosed
US-6255449-B1 PROCESS FOR PREPARING POLYMERS HAVING AT LEAST THREE FLUORENE GROUPS IN BACKBONE, WHICH COMPRISES HEATING 2,7-DIHALO-9-SUBSTITUTED FLUORENES UNDER REACTION CONDITIONS SUFFICIENT TO FORM SAID POLYMERS THE DOW CHEMICAL COMPANY 2001-07-03 US disclosed
US-6169163-B1 NOVEL 2,7-DIHALOFLUORENES SUBSTITUTED AT 9-POSITION THE DOW CHEMICAL COMPANY 2001-01-02 US disclosed
WO-2000046321-A1 FLUORENE COPOLYMERS AND DEVICES MADE THEREFROM THE DOW CHEMICAL COMPANY (US) 2000-08-10 WO disclosed