SCHEMBL1670299

SCHEMBL1670299

Clc1ccc2c(c1)=N[N]N=2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.38
CYP2A6 P11509 2/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 7/20 0.35
ALDH1A1 P00352 5/20 0.35
CYP3A4 P08684 3/20 0.35
ALOX15 P16050 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
DYRK1A Q13627 2/20 0.34
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
HSD17B10 Q99714 4/20 0.33
HPGD P15428 2/20 0.33
POLB P06746 1/20 0.33
PSMB8 P28062 1/20 0.33
HAVCR2 Q8TDQ0 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
AHR P35869 1/20 0.33
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7111914 0.67 TP53 (0.36) TP53CYP2A6LMNATSHRALDH1A1
SCHEMBL28566219 0.67 TP53 (0.36) TP53CYP2A6LMNATSHRALDH1A1
SCHEMBL3226561 0.65 S100A4 (0.39) TP53LMNATSHRALDH1A1HPGD
1,4-Dichlorobenzene SCHEMBL27770187 0.61
1,4-Dichlorobenzene SCHEMBL5144812 0.61 LMNA (0.89) TP53CYP2A6LMNATSHRALDH1A1
SCHEMBL22719966 0.57 TP53 (0.32) TP53TSHRALDH1A1CYP3A4ALOX15
Ammonia Solution, Strong SCHEMBL2163448 0.57
Ammonia Solution, Strong SCHEMBL11828318 0.57 TSHR (0.58) CYP2A6LMNATSHRALDH1A1CYP3A4
SCHEMBL54901 0.57
SCHEMBL865990 0.57 CYP2A6 (0.77) TP53CYP2A6LMNATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023108588-A1 PROCESS FOR PRODUCING CABLE WITH INSULATION LAYER DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-22 WO disclosed
WO-2023108586-A1 OLEFIN/SILANE INTERPOLYMER COMPOSITIONS WITH EXCELLENT THERMAL OXIDATION RESISTANCE DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-22 WO disclosed
US-20220194907-A1 PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2022-06-23 US disclosed
US-11259524-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-01 US disclosed
EP-3157988-B1 LIGHT TRANSPARENT FLUOROPOLYMER COMPOSITION AND ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-12-01 EP disclosed
US-11110689-B2 Pressure sensitive adhesive composition including ultraviolet light-absorbing oligomer 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
US-20210037826-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-02-11 US disclosed
US-10836883-B2 Light transparent fluoropolymer composition and article 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-17 US disclosed
US-10798941-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2020-10-13 US disclosed
EP-3313906-B1 COPOLYMER INCLUDING ULTRAVIOLET LIGHT-ABSORBING GROUP AND COMPOSITIONS INCLUDING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2020-08-05 EP disclosed
US-20150337096-A1 FLUOROPOLYMER COMPOSITION INCLUDING AN OLIGOMER HAVING AN ULTRAVIOLET ABSORBING GROUP 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-11-26 US disclosed
EP-2935472-A1 FLUOROPOLYMER COMPOSITION INCLUDING AN OLIGOMER HAVING AN ULTRAVIOLET ABSORBING GROUP 3M Innovative Properties Company (US) 2015-10-28 EP disclosed
EP-2935373-A1 COPOLYMERS INCLUDING ULTRAVIOLET ABSORBING GROUPS AND FLUOROPOLYMER COMPOSITIONS INCLUDING THEM 3M Innovative Properties Company (US) 2015-10-28 EP disclosed
WO-2014193550-A1 METHODS OF LAYER BY LAYER SELF-ASSEMBLY OF A POLYELECTROLYTE COMPRISING LIGHT ABSORBING OR STABILIZING COMPOUND AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-12-04 WO disclosed
WO-2014100580-A1 FLUOROPOLYMER COMPOSITION INCLUDING AN OLIGOMER HAVING AN ULTRAVIOLET ABSORBING GROUP 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-06-26 WO disclosed
WO-2014100551-A1 COPOLYMERS INCLUDING ULTRAVIOLET ABSORBING GROUPS AND FLUOROPOLYMER COMPOSITIONS INCLUDING THEM 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-06-26 WO disclosed
EP-2486097-A1 CROSS-LINKABLE COMPOSITIONS Wacker Chemie AG (DE) 2012-08-15 EP disclosed
WO-2011042340-A1 CROSS-LINKABLE COMPOSITIONS WACKER CHEMIE AG (DE) 2011-04-14 WO disclosed
US-RE28760-E Photographic element including superimposed silver halide layers of different speeds EASTMAN KODAK COMPANY (US) 1976-04-06 US disclosed
US-3935015-A Silver halide color photographic materials containing 3-anilino-5-pyrazolane couplers FUJI PHOTO FILM CO., LTD. (JA) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210037826-A1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES PRF1, NOX1, ARG1 TP53 2838/4885CYP2A6 452/4885LMNA 4450/4885
US-10798941-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG1 TP53 2660/4885CYP2A6 530/4885LMNA 4546/4885
US-11259524-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG1 TP53 2838/4885CYP2A6 452/4885LMNA 4450/4885
US-20220194907-A1 PROCESS FOR THE PREPARATION OF MICROBIOCIDAL OXADIAZOLE DERIVATIVES CYP51A1, MPO, NOX5 TP53 4335/4885CYP2A6 362/4885LMNA 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.