Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | BRD2 | P25440 | 2/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670212 | 0.74 | PTGS2 (0.44) | PTGS2MAPTALDH1A1BRD4MEN1 | |
| SCHEMBL1672794 | 0.72 | PTGS2 (0.44) | PTGS2MAPTBRD4BRD2BRD3 | |
| SCHEMBL12987843 | 0.71 | TUBB4A (0.40) | PTGS2ALDH1A1BRD4BRD2BRD3 | |
| SCHEMBL12985937 | 0.71 | TUBB4A (0.46) | PTGS2MAPTALDH1A1BRD4 | |
| SCHEMBL12800447 | 0.68 | PTGS2 (0.41) | PTGS2MAPTALDH1A1BRD4BRD2 | |
| SCHEMBL12800962 | 0.68 | PTGS2 (0.40) | PTGS2MAPTBRD4 | |
| SCHEMBL12986522 | 0.67 | TUBB4A (0.44) | MAPTALDH1A1BRD4 | |
| SCHEMBL17833811 | 0.66 | PTGS2 (0.72) | PTGS2MAPTBRD4BRD2BRD3 | |
| SCHEMBL13195254 | 0.66 | PTGS2 (0.41) | PTGS2MAPTALDH1A1BRD4TDP1 | |
| SCHEMBL1672841 | 0.66 | MAOA (0.39) | PTGS2MAPTALDH1A1BRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |