Sugi Predict

Sugi Predict / Compounds / SCHEMBL1670447

SCHEMBL1670447

SCHEMBL1670447

COC(=O)[C@H]1CC[C@H](CN)CC1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PLG P00747 1/20 0.57
▸ PLAT P00750 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ F2 P00734 1/20 0.44
▸ TP53 P04637 1/20 0.43
▸ ALDH1A1 P00352 2/20 0.41
▸ GAA P10253 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ CYP2D6 P10635 1/20 0.39
▸ CHRNB2 P17787 2/20 0.38
▸ CHRNA4 P43681 2/20 0.38
▸ CHRNB4 P30926 1/20 0.38
▸ CHRNA3 P32297 1/20 0.38
▸ CHRNA7 P36544 1/20 0.38
▸ POLB P06746 1/20 0.38
▸ HPGD P15428 1/20 0.37
▸ KLKB1 P03952 1/20 0.36
▸ PPM1B O75688 1/20 0.36
▸ PTPN1 P18031 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13163197 1.00 PLG (0.57) PLGPLATLMNAF2TP53
SCHEMBL1233032 1.00 PLG (0.57) PLGPLATLMNAF2TP53
Hydrochloric Acid SCHEMBL1700731 0.98 PLG (0.55) PLGPLATLMNAF2TP53
Hydrochloric Acid SCHEMBL1233030 0.98 PLG (0.55) PLGPLATLMNAF2TP53
Hydrochloric Acid SCHEMBL11893771 0.96 PLG (0.53) PLGPLATLMNAF2TP53
Hydrochloric Acid SCHEMBL1666998 0.96 PLG (0.53) PLGPLATLMNAF2TP53
SCHEMBL9294135 0.88 ALDH1A1 (0.46) PLGPLATLMNAF2TP53
SCHEMBL6011646 0.84 ALDH1A1 (0.46) PLGPLATLMNATP53ALDH1A1
SCHEMBL358775 0.83 GAA (0.47) TP53ALDH1A1GAASMN1; SMN2CHRNB2
SCHEMBL5543322 0.83 GAA (0.47) TP53ALDH1A1GAASMN1; SMN2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113842378-B Tranexamic acid patch and preparation method thereof 南通新世元生物科技有限公司 2023-11-24 — — CN claimed
JP-56125342-A — — None — — JP disclosed
EP-4634169-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF Pfizer Inc. (US) 2025-10-22 — — EP disclosed
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-10-16 — — US disclosed
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA INC (US) 2025-04-24 — — US disclosed
WO-2025059577-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS FOR USE AS AKT1 INHIBITORS ATAVISTIK BIO, INC. (US) 2025-03-20 — — WO disclosed
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders PFIZER INC. (US) 2024-07-18 — — US disclosed
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders PFIZER INC. (US) 2024-07-18 — — US disclosed
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders PFIZER INC. (US) 2024-07-18 — — US disclosed
WO-2024127297-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF PFIZER INC. (US) 2024-06-20 — — WO disclosed
US-20060276464-A1 Diarylsulfone sulfonamides and use thereof WYETH (US) 2006-12-07 — — US disclosed
WO-2006088711-A1 AZOLYLACYLGUANIDINES AS β-SECRETASE INHIBITORS WYETH (US) 2006-08-24 — — WO disclosed
WO-2004073709-A1 ANTIMICROBIAL AGENTS PROLYSIS LIMITED (GB) 2004-09-02 — — WO disclosed
US-6627767-B2 Controlling cellular metabolism ABBOTT LABORATORIES 2003-09-30 — — US disclosed
US-20020035136-A1 Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors ABBVIE INC. 2002-03-21 — — US disclosed
WO-2002018321-A2 AMINO(OXO)ACETIC ACID PROTEIN TYROSINE PHOSPHATASE INHIBITORS ABBOTT LABORATORIES (US) 2002-03-07 — — WO disclosed
US-5922717-A ANTICOAGULANTS DR. KARL THOMAE GMBH (DE) 1999-07-13 — — US disclosed
EP-0055145-B1 4-(AMINOMETHYL)CYCLOHEXANE-1-CARBOXYLIC ACID DERIVATIVES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-12-05 — — EP disclosed
US-4387102-A 4-(N-(3',4'-Methylenedioxybenzylidene)-aminomethyl)cyclohexane-1-carboxylic acid and derivatives thereof and pharmaceutical composition thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-06-07 — — US disclosed
JP-S56125342-A PREPARATION OF EE-TYPE MONO-SUBSTITUTED CYCLOHEXANE-1- CARBOXYLIC ACID ESTER KANTO KAGAKU KK 1981-10-01 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238425-A1 HSD17B13 Inhibitors and/or Degraders HSD17B13, HSD17B3, HSD17B1 PLG 1797/4885PLAT 3257/4885LMNA 1598/4885
US-20250129085-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 PLG 2785/4885PLAT 1809/4885LMNA 2351/4885
US-20020035136-A1 Amino(oxo) acetic acid protein tyrosine phosphatase inhibitors PPM1A, PPM1F, PPM1G PLG 4808/4885PLAT 4102/4885LMNA 4803/4885
US-20060276464-A1 Diarylsulfone sulfonamides and use thereof SFRP1, SOS1, FZD7 PLG 4778/4885PLAT 4604/4885LMNA 4608/4885
US-20250320217-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 PLG 2785/4885PLAT 1809/4885LMNA 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback