SCHEMBL5358221

SCHEMBL5358221

CCOC(=O)OCC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
KDM4E B2RXH2 9/20 0.41
CYP2C19 P33261 4/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C9 P11712 1/20 0.36
MAPK1 P28482 2/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
SOAT1 P35610 1/20 0.35
POLB P06746 1/20 0.35
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21646820 1.00 ALDH1A1 (0.42) ALDH1A1KDM4ECYP2C19CYP3A4CYP2C9
SCHEMBL4401217 0.92 KDM4E (0.39) ALDH1A1KDM4EMAPK1MAPTPKM
SCHEMBL14434848 0.92 KDM4E (0.39) ALDH1A1KDM4EMAPK1MAPTPKM
SCHEMBL5359702 0.88 KDM4E (0.39) ALDH1A1KDM4EMAPK1MAPTPKM
SCHEMBL6537287 0.87 KDM4E (0.41) ALDH1A1KDM4ECYP2C19CYP3A4MAPK1
SCHEMBL5349663 0.85 KDM4E (0.39) ALDH1A1KDM4EMAPK1MAPTPKM
SCHEMBL5358599 0.85 KDM4E (0.38) ALDH1A1KDM4ECYP2C19MAPK1MAPT
SCHEMBL16704804 0.83 KDM4E (0.38) ALDH1A1KDM4ECYP2C19CYP3A4MAPK1
SCHEMBL16705148 0.83 KDM4E (0.38) ALDH1A1KDM4ECYP2C19CYP3A4MAPK1
SCHEMBL457240 0.82 KDM4E (0.41) ALDH1A1KDM4EMAPK1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230146062-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS PROMERUS, LLC (US) 2023-05-11 US claimed
US-11584899-B2 Fragrance compositions containing norbornene derivatives for personal care products PROMERUS, LLC (US) 2023-02-21 US claimed
WO-2021146495-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS PROMERUS, LLC (US) 2021-07-22 WO claimed
US-20210214642-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS PROMERUS, LLC (US) 2021-07-15 US claimed
EP-3824054-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES Promerus, LLC (US) 2021-05-26 EP claimed
WO-2020018485-A2 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES PROMERUS, LLC (US) 2020-01-23 WO claimed
US-11834622-B2 Fragrance compositions containing norbornene derivatives for personal care products PROMERUS, LLC (US) 2023-12-05 US disclosed
US-11834622-B2 Fragrance compositions containing norbornene derivatives for personal care products PROMERUS, LLC (US) 2023-12-05 US disclosed
US-20230146062-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS PROMERUS, LLC (US) 2023-05-11 US disclosed
US-20230146062-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS PROMERUS, LLC (US) 2023-05-11 US disclosed
US-20230146062-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS PROMERUS, LLC (US) 2023-05-11 US disclosed
US-11584899-B2 Fragrance compositions containing norbornene derivatives for personal care products PROMERUS, LLC (US) 2023-02-21 US disclosed
US-11584899-B2 Fragrance compositions containing norbornene derivatives for personal care products PROMERUS, LLC (US) 2023-02-21 US disclosed
EP-1021750-A1 PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS THE B.F. GOODRICH COMPANY (US) 2000-07-26 EP disclosed
EP-1021477-A1 PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS THE B.F. GOODRICH COMPANY (US) 2000-07-26 EP disclosed
WO-1999042510-A1 MODIFIED POLYCYCLIC POLYMERS THE B.F. GOODRICH COMPANY (US) 1999-08-26 WO disclosed
WO-1999014635-A1 PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS THE B.F. GOODRICH COMPANY (US) 1999-03-25 WO disclosed
WO-1999014256-A1 PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS THE B.F. GOODRICH COMPANY (US) 1999-03-25 WO disclosed
EP-0885405-A1 PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS THE B.F. GOODRICH COMPANY (US) 1998-12-23 EP disclosed
WO-1997033198-A1 PHOTORESIST COMPOSITIONS COMPRISING POLYCYCLIC POLYMERS WITH ACID LABILE PENDANT GROUPS THE B.F. GOODRICH COMPANY (US) 1997-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230146062-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS POLR1C, CYP1B1, CUTA ALDH1A1 89/4885KDM4E 3671/4885CYP2C19 743/4885
US-11584899-B2 Fragrance compositions containing norbornene derivatives for personal care products POLR1C, CYP1B1, CUTA ALDH1A1 89/4885KDM4E 3671/4885CYP2C19 743/4885
US-11834622-B2 Fragrance compositions containing norbornene derivatives for personal care products POLR1C, CYP1B1, CUTA ALDH1A1 89/4885KDM4E 3671/4885CYP2C19 743/4885
US-20210214642-A1 FRAGRANCE COMPOSITIONS CONTAINING NORBORNENE DERIVATIVES FOR PERSONAL CARE PRODUCTS POLR1C, CYP1B1, CUTA ALDH1A1 89/4885KDM4E 3671/4885CYP2C19 743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.