Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198548 | 0.83 | MAPT (0.57) | ALDH1A1MAPTSIGMAR1L3MBTL1DRD4 | |
| SCHEMBL11309685 | 0.83 | MAPT (0.47) | ALDH1A1MAPTSIGMAR1L3MBTL1ROCK2 | |
| SCHEMBL18660246 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1ROCK2ROCK1 | |
| SCHEMBL8695957 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTSIGMAR1L3MBTL1ROCK2 | |
| SCHEMBL11307296 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1RORCDRD4 | |
| SCHEMBL171395 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1KMT2ACYP2C19 | |
| SCHEMBL11322171 | 0.79 | ROCK2 (0.57) | ALDH1A1MAPTSIGMAR1L3MBTL1ROCK2 | |
| SCHEMBL11318906 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL11315429 | 0.78 | ROCK2 (0.56) | ALDH1A1MAPTSIGMAR1L3MBTL1ROCK2 | |
| SCHEMBL52481 | 0.77 | MAPT (0.64) | ALDH1A1MAPTSIGMAR1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-B1 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2015-05-13 | — | — | EP | disclosed |