Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLEC | Q15149 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629284 | 0.87 | MAPT (0.59) | MAPTHTTHRH3KDM4EMAPK1 | |
| SCHEMBL16705249 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AL3MBTL1DRD4 | |
| SCHEMBL81430 | 0.80 | MAPT (0.67) | MAPTHTTHRH3KDM4EMAPK1 | |
| SCHEMBL409332 | 0.78 | MAPT (0.76) | MAPTHTTHRH3KDM4EMAPK1 | |
| SCHEMBL9364512 | 0.77 | MAPT (0.61) | MAPTHTTMEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL2860788 | 0.76 | MAPT (0.73) | MAPTHTTHRH3KDM4EMAPK1 | |
| SCHEMBL2065837 | 0.75 | MAPT (1.00) | MAPTHTTHRH3KDM4EMAPK1 | |
| SCHEMBL5157848 | 0.75 | APP (0.44) | MAPTHTTHRH3MAPK1ALDH1A1 | |
| SCHEMBL1485752 | 0.74 | MAPT (0.70) | MAPTHTTHRH3KDM4EMAPK1 | |
| SCHEMBL10887423 | 0.74 | LMNA (0.43) | HRH3KDM4EMAPK1BLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010328-A1 | 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES | 덕성여자대학교 산학협력단 | 2022-01-13 | — | — | WO | disclosed |