Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 2/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170344 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1TOP2AKMT2A | |
| SCHEMBL12337252 | 0.83 | MAPT (0.52) | ALDH1A1MAPTCYP2C19NCF1MALT1 | |
| SCHEMBL27644720 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP2C19NCF1L3MBTL1 | |
| SCHEMBL5724876 | 0.80 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MEN1KMT2AHTR2A | |
| SCHEMBL10798745 | 0.80 | TAAR1 (0.52) | MAPTCYP2C19TAAR1MEN1KMT2A | |
| SCHEMBL81430 | 0.80 | MAPT (0.67) | ALDH1A1MAPTCYP2C19L3MBTL1MEN1 | |
| SCHEMBL16705249 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTCYP2C19NCF1L3MBTL1 | |
| SCHEMBL11695249 | 0.79 | MAPT (0.48) | ALDH1A1MAPTCYP2C19NCF1MALT1 | |
| SCHEMBL8900599 | 0.79 | SIGMAR1 (0.58) | ALDH1A1MAPTL3MBTL1TAAR1MEN1 | |
| SCHEMBL4171220 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTCYP2C19L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101273016-B | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV | 2013-01-02 | — | — | CN | claimed |
| CN-101273016-A | Antibacterial quinoline derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | CN | claimed |
| CN-119707835-A | 2-Aminopyrimidine-5-carboxamide compounds and use thereof for the production of medicaments for the treatment and/or prophylaxis of cancer | 沈阳药科大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-117285455-A | 2-benzoyl indole compounds and application thereof | 江苏开元药业有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-110914238-B | Compounds as antibiotics | 安塔比奥公司 | 2023-06-20 | — | — | CN | disclosed |
| US-11345711-B2 | 8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-ones | Impact Therapeutics (Shanghai), Inc (CN) | 2022-05-31 | — | — | US | disclosed |
| US-20200385394-A1 | 8,9-DIHYDROIMIDAZO[1,2-a]PYRIMIDO[5,4-e]PYRIMIDIN-5(6H)-ONES | Impact Therapeutics (Shanghai), Inc (CN) | 2020-12-10 | — | — | US | disclosed |
| US-10703759-B2 | 8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-ones | IMPACT THERAPEUTICS, INC (CN) | 2020-07-07 | — | — | US | disclosed |
| US-20190308984-A1 | 8,9-DIHYDROIMIDAZO[1,2-a]PYRIMIDO[5,4-e]PYRIMIDIN-5(6H)-ONES | Impact Therapeutics (Shanghai), Inc (CN) | 2019-10-10 | — | — | US | disclosed |
| US-10301267-B2 | Compounds | ASTRAZENECA AB (SE) | 2019-05-28 | — | — | US | disclosed |
| US-20170260143-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2017-09-14 | — | — | US | disclosed |
| US-4594343-A | FOR DEEP FAT FRYING VAT OIL; REMOVING CONTAMINANTS; RESTAURANTS | A.H. ROBINS COMPANY, INCORPORATED, A DE CORP. | 1986-06-10 | — | — | US | disclosed |
| EP-0178947-A2 | 1-[(Aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl]-alpha,alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-04-23 | — | — | EP | disclosed |
| EP-0084292-B1 | N,N-DISUBSTITUTED ALKENAMIDES AND PHENYLALKENAMIDES, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICALS | SANDOZ AG (CH) | 1985-02-13 | — | — | EP | disclosed |
| EP-0049779-B1 | 3-AMINOINDAZOLE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |
| EP-0084292-A1 | N,N-disubstituted alkenamides and phenylalkenamides, processes for their production and their use as pharmaceuticals | SANDOZ AG (CH) | 1983-07-27 | — | — | EP | disclosed |
| US-4333930-A | TREATMENT OF CENTRAL NERVOUS DISORDERS, ANALGESICS, ANTIDEPRESSANTS | LABORATOIRES SARGET (FR) | 1982-06-08 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
| US-4002631-A | HEAT-SENSITIVE COLOR FORMERS | HODOGAYA CHEMICAL CO., LTD. (JA) | 1977-01-11 | — | — | US | disclosed |
| US-3992405-A | ESPECIALLY FOR DYEING POLYACRYLIC FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301267-B2 | Compounds | SLC10A1, CYP11B1, ABCB11 | ALDH1A1 78/4885MAPT 2665/4885CYP2C19 64/4885 |
| US-20190308984-A1 | 8,9-DIHYDROIMIDAZO[1,2-a]PYRIMIDO[5,4-e]PYRIMIDIN-5(6H)-ONES | WEE1, WEE2, CCNE1 | ALDH1A1 1361/4885MAPT 4062/4885CYP2C19 1541/4885 |
| US-11345711-B2 | 8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-ones | WEE1, WEE2, CCNE1 | ALDH1A1 1361/4885MAPT 4062/4885CYP2C19 1541/4885 |
| US-10703759-B2 | 8,9-dihydroimidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-ones | WEE1, WEE2, CCNE1 | ALDH1A1 1361/4885MAPT 4062/4885CYP2C19 1541/4885 |
| US-20170260143-A1 | NOVEL COMPOUNDS | SLC10A1, ABCB11, CYP11B1 | ALDH1A1 338/4885MAPT 3418/4885CYP2C19 761/4885 |
| US-20200385394-A1 | 8,9-DIHYDROIMIDAZO[1,2-a]PYRIMIDO[5,4-e]PYRIMIDIN-5(6H)-ONES | WEE1, WEE2, CCNE1 | ALDH1A1 1361/4885MAPT 4062/4885CYP2C19 1541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.