Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036204 | 0.86 | GPR119 (0.61) | GPR119 | |
| SCHEMBL12071830 | 0.79 | GPR119 (0.58) | GPR119 | |
| SCHEMBL1118249 | 0.79 | GPR119 (0.58) | GPR119SMN1; SMN2 | |
| SCHEMBL13634287 | 0.75 | ERBB2 (0.39) | GPR119DRD2HTR2AHRH1SLC6A3 | |
| SCHEMBL20040544 | 0.74 | GPR119 (0.53) | GPR119OGA | |
| SCHEMBL12387815 | 0.74 | SLC6A3 (0.47) | GPR119DRD2HTR2AHRH1SLC6A3 | |
| SCHEMBL18714938 | 0.72 | HRH3 (0.39) | GPR119OGACETPALDH1A1HRH4 | |
| SCHEMBL1364634 | 0.72 | SLC6A3 (0.40) | GPR119DRD2HTR2ASLC6A3ALDH1A1 | |
| SCHEMBL12771442 | 0.72 | ACHE (0.45) | GPR119OGAALDH1A1HRH4HRH3 | |
| SCHEMBL13634289 | 0.71 | DRD2 (0.46) | DRD2HTR2AHRH1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280704-B1 | OXYMETHYLENE ARYL COMPOUNDS AND USES THEREOF | CYMABAY THERAPEUTICS INC (US) | 2015-05-13 | — | — | EP | disclosed |