SCHEMBL16706705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16706771	0.93	TDP1 (0.42)	OGANPC1RAB9ABCHETDP1
	SCHEMBL16706691	0.92	KMT2A (0.50)	OGANPC1RAB9ABCHETDP1
	SCHEMBL18939746	0.92	OGA (0.47)	OGANPC1RAB9ABCHETSHR
	SCHEMBL16706677	0.90	NPC1 (0.50)	NPC1RAB9ABCHETDP1FAAH
	SCHEMBL16706687	0.90	MMP1 (0.45)	OGATSHRMMP1MMP13MMP2
	SCHEMBL16706669	0.89	MMP1 (0.45)	OGATDP1FAAHTSHRMMP1
	SCHEMBL16706789	0.88	MEN1 (0.52)	NPC1RAB9ATDP1FAAHLMNA
	SCHEMBL16710024	0.88	TDP1 (0.57)	NPC1TDP1FAAHTSHRL3MBTL1
	SCHEMBL16706708	0.88	TAS1R3 (0.54)	FAAHTSHRMMP1MMP13MMP2
	SCHEMBL16706793	0.86	FAAH (0.51)	NPC1RAB9ATDP1FAAHMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.