Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668333 | 0.82 | RXRA (0.35) | RXRAFFAR1FFAR4 | |
| SCHEMBL12800418 | 0.77 | OPRM1 (0.40) | RXRAITGB3ITGA2BFFAR1TACR1 | |
| Trifluoroacetic Acid SCHEMBL1668669 | 0.77 | APP (0.35) | RXRAFFAR1FFAR4TACR1 | |
| Trifluoroacetic Acid SCHEMBL1668616 | 0.73 | FFAR4 (0.43) | FFAR1FFAR4TACR1 | |
| Trifluoroacetic Acid SCHEMBL1670826 | 0.67 | ITGB3 (0.41) | ITGB3ITGA2BTACR1 | |
| Trifluoroacetic Acid SCHEMBL1670822 | 0.67 | ITGB3 (0.42) | ITGB3ITGA2BTACR1 | |
| SCHEMBL12800404 | 0.65 | CHRM5 (0.40) | RXRAFFAR1 | |
| SCHEMBL12801191 | 0.64 | CHRM5 (0.46) | RXRA | |
| SCHEMBL1668619 | 0.63 | FFAR4 (0.35) | FFAR1FFAR4TACR1 | |
| SCHEMBL1668419 | 0.63 | RXRA (0.38) | RXRAFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |