Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1668616 | 0.89 | FFAR4 (0.43) | FFAR4FFAR1TACR1 | |
| Hydrochloric Acid SCHEMBL1668222 | 0.81 | FFAR1 (0.43) | FFAR4FFAR1TACR1 | |
| SCHEMBL1670735 | 0.75 | CHRM5 (0.46) | FFAR4FFAR1 | |
| SCHEMBL12801209 | 0.75 | OPRD1 (0.47) | FFAR4TACR1 | |
| SCHEMBL12800418 | 0.74 | OPRM1 (0.40) | FFAR1TACR1 | |
| SCHEMBL12801208 | 0.73 | FFAR4 (0.47) | FFAR4FFAR1 | |
| SCHEMBL12800828 | 0.73 | OPRD1 (0.39) | FFAR4FFAR1TACR1 | |
| SCHEMBL1670831 | 0.73 | SMN1; SMN2 (0.36) | TACR1 | |
| SCHEMBL1670823 | 0.72 | ITGB3 (0.36) | TACR1 | |
| SCHEMBL1669343 | 0.71 | OPRD1 (0.40) | FFAR4FFAR1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |