Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD2 | P25440 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670700 | 0.85 | ERN1 (0.40) | BRD4ALDH1A1BRD2TAS2R8 | |
| SCHEMBL1670708 | 0.81 | PTGS2 (0.43) | PTGS2MAPTBRD4ALDH1A1MEN1 | |
| SCHEMBL1544992 | 0.75 | ALDH1A1 (0.47) | PTGS2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1670212 | 0.71 | PTGS2 (0.44) | PTGS2MAPTBRD4ALDH1A1MEN1 | |
| SCHEMBL12800445 | 0.68 | PTGS2 (0.42) | PTGS2MAPTBRD4ALDH1A1KDM4E | |
| SCHEMBL1672802 | 0.68 | RAB9A (0.39) | PTGS2MAPTBRD4KMT2ARAB9A | |
| SCHEMBL12800447 | 0.68 | PTGS2 (0.41) | PTGS2MAPTBRD4ALDH1A1HPGD | |
| SCHEMBL20547398 | 0.67 | MAPT (0.39) | MAPTBRD4ALDH1A1KMT2AKDM4E | |
| SCHEMBL12800962 | 0.67 | PTGS2 (0.40) | PTGS2MAPTBRD4HPGDRAB9A | |
| SCHEMBL1672794 | 0.66 | PTGS2 (0.44) | PTGS2MAPTBRD4RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |