SCHEMBL1670731

SCHEMBL1670731

Cc1noc(C)c1-n1c(C#N)c(C)c(Cl)c1-c1ccc(O)cc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 4/20 0.34
AR P10275 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1670583 0.86 MAOA (0.38) BRD4
SCHEMBL12800989 0.82 BRD4 (0.35) BRD4
SCHEMBL12986067 0.80 ALDH1A1 (0.35) BRD4AR
SCHEMBL1670941 0.76 BRD4 (0.32) BRD4
SCHEMBL1670939 0.76 BRD4 (0.32) BRD4
SCHEMBL1672841 0.74 MAOA (0.39) BRD4
SCHEMBL12800442 0.70 BRD4 (0.33) BRD4
SCHEMBL12800962 0.68 PTGS2 (0.40) BRD4
SCHEMBL12800991 0.67 BRD4 (0.32) BRD4
SCHEMBL12986874 0.67 CREBBP (0.39) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011042477-A1 SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS KARO BIO AB (SE) 2011-04-14 WO disclosed