Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12153680 | 0.89 | ALDH1A1 (0.49) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL17880401 | 0.85 | ALDH1A1 (0.36) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL22354571 | 0.84 | USP2 (0.62) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL1245084 | 0.83 | USP2 (0.46) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL12153682 | 0.82 | ALDH1A1 (0.43) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL15536318 | 0.82 | USP2 (0.45) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL12761114 | 0.81 | USP2 (0.59) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL20487113 | 0.81 | USP2 (0.67) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL13394456 | 0.80 | ALDH1A1 (0.40) | USP2ALDH1A1TSHRHTTL3MBTL1 | |
| SCHEMBL12153683 | 0.80 | KDM4E (0.47) | USP2ALDH1A1TSHRHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9925521-B2 | Chromatographic materials | WATERS TECHNOLOGIES CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-20150133294-A1 | CHROMATOGRAPHIC MATERIALS | WATERS TECHNOLOGIES CORPORATION (US) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133294-A1 | CHROMATOGRAPHIC MATERIALS | HAX1, CXCR1, YBX1 | USP2 2648/4885ALDH1A1 1859/4885TSHR 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.