Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884282 | 0.90 | ALDH1A1 (0.36) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL16707883 | 0.85 | USP2 (0.47) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL15535436 | 0.75 | KMT2A (0.46) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL12153680 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL16724866 | 0.74 | KMT2A (0.51) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL16707875 | 0.74 | KMT2A (0.51) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL16724862 | 0.74 | KMT2A (0.51) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL15535022 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL12153683 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL13705970 | 0.71 | KDM4E (0.48) | ALDH1A1KDM4EUSP2ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160184736-A1 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | WATERS TECHNOLOGIES CORPORATION (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184736-A1 | CHROMATOGRAPHIC COLUMNS AND SEPARATION DEVICES COMPRISING A SUPERFICIALLY POROUS MATERIAL; AND USE THEREOF FOR SUPERCRITICAL FLUID CHROMATOGRAPHY AND OTHER CHROMATOGRAPHY | SPECC1L, CCL5, CCR5 | ALDH1A1 3401/4885KDM4E 3622/4885USP2 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.