Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1671716 | 0.82 | GRIA2 (0.41) | GRIA4GAAALDH1A1KDM4ELMNA | |
| SCHEMBL12801011 | 0.80 | SENP1 (0.36) | ARSENP1GAAALDH1A1ALOX15 | |
| SCHEMBL1670503 | 0.73 | AR (0.39) | ARGRIA4MMP3SENP1GAA | |
| SCHEMBL1670817 | 0.72 | MLYCD (0.40) | ARBRD4 | |
| SCHEMBL1670563 | 0.69 | GRIA4 (0.39) | ARGRIA4SENP1ALDH1A1KDM4E | |
| SCHEMBL10591364 | 0.66 | GRIA4 (0.42) | ARGRIA4GAAALDH1A1MAPK1 | |
| SCHEMBL12800399 | 0.64 | SENP1 (0.36) | ARSENP1GAAALDH1A1ESR2 | |
| Acetonitrile SCHEMBL28239695 | 0.59 | ESR1 (0.65) | ARMMP3SENP1ALDH1A1KDM4E | |
| SCHEMBL8873272 | 0.58 | DYRK1A (0.30) | — | |
| SCHEMBL1457230 | 0.58 | ESR1 (0.71) | MMP3SENP1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |