SCHEMBL16709153

SCHEMBL16709153

C[C@@H]1Oc2ccccc2N1CN1c2ccccc2O[C@@H]1C

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTT P42858 1/20 0.36
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
P2RX4 Q99571 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11688375 0.84 NISCH (0.37) TSHRALDH1A1L3MBTL1HTTADRA2B
SCHEMBL25415493 0.81 BRD4 (0.47) TSHRHTTMEN1KMT2A
SCHEMBL20027221 0.74 GPR3 (0.39) TSHRALDH1A1L3MBTL1HTTCHRNB4
SCHEMBL16728888 0.74 GPR3 (0.39) TSHRALDH1A1L3MBTL1HTTCHRNB4
SCHEMBL21901747 0.72 P2RX4 (0.34) TSHRALDH1A1L3MBTL1HTTCHRNB4
SCHEMBL16726437 0.69 TSHR (0.33) TSHRALDH1A1L3MBTL1HTTCHRNB4
SCHEMBL15779871 0.69 MAOA (0.38) TSHRALDH1A1L3MBTL1HTTADRA1D
SCHEMBL16726511 0.69 TSHR (0.33) TSHRALDH1A1L3MBTL1HTTCHRNB4
SCHEMBL18706207 0.69 P2RX4 (0.36) TSHRALDH1A1L3MBTL1HTTMEN1
SCHEMBL18876528 0.68 ALDH1A1 (0.39) ALDH1A1L3MBTL1HTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9306179-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-05 US disclosed
US-9306179-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-05 US disclosed
US-20150129840-A1 OSMIUM COMPLEXES COMPRISING THREE DIFFERENT BIDENTATE LIGANDS AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-05-14 US disclosed
US-20150129840-A1 OSMIUM COMPLEXES COMPRISING THREE DIFFERENT BIDENTATE LIGANDS AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-05-14 US disclosed