SCHEMBL21901747

SCHEMBL21901747

C[C@H]1Oc2ccccc2N1I

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 1/20 0.34
CHRNB4 P30926 2/20 0.34
CHRNA3 P32297 2/20 0.34
TSHR P16473 2/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16728888 0.76 GPR3 (0.39) P2RX4CHRNB4CHRNA3TSHRCHRNB2
SCHEMBL20027221 0.76 GPR3 (0.39) P2RX4CHRNB4CHRNA3TSHRCHRNB2
SCHEMBL16709153 0.72 TSHR (0.36) P2RX4CHRNB4CHRNA3TSHRALDH1A1
SCHEMBL16726437 0.71 TSHR (0.33) P2RX4CHRNB4CHRNA3TSHRCHRNB2
SCHEMBL18706207 0.71 P2RX4 (0.36) P2RX4CHRNB4CHRNA3TSHRCHRNB2
SCHEMBL16726511 0.71 TSHR (0.33) P2RX4CHRNB4CHRNA3TSHRCHRNB2
SCHEMBL15779871 0.71 MAOA (0.38) P2RX4CHRNB4CHRNA3TSHRCHRNB2
Iodide SCHEMBL11688375 0.69 NISCH (0.37) P2RX4TSHRALDH1A1L3MBTL1HTT
SCHEMBL18876528 0.69 ALDH1A1 (0.39) ALDH1A1L3MBTL1HTTSMN1; SMN2
SCHEMBL8525523 0.68 POLB (0.43) PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3220441-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2020-04-22 EP disclosed