Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1672794 | 0.81 | PTGS2 (0.44) | MAPTSMN1; SMN2PTGS2 | |
| SCHEMBL1671504 | 0.76 | ERN1 (0.36) | AMY1AFFAR1MAPTSMN1; SMN2TTR | |
| SCHEMBL10340365 | 0.66 | AMY1A (0.50) | AMY1AMAPTALDH1A1PRKAB2PRKAG1 | |
| SCHEMBL12988942 | 0.66 | AMY1A (0.44) | AMY1AMAPTSMN1; SMN2ALDH1A1PRKAB2 | |
| SCHEMBL1670212 | 0.63 | PTGS2 (0.44) | MAPTSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL13791166 | 0.62 | CYP2C19 (0.50) | AMY1ASMN1; SMN2 | |
| SCHEMBL19387237 | 0.62 | AMY1A (0.46) | AMY1APTGS1PTGS2ALDH1A1PRKAB2 | |
| SCHEMBL15666746 | 0.62 | DRD1 (0.53) | AMY1APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL20547398 | 0.62 | MAPT (0.39) | MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL10014160 | 0.61 | CYP2C19 (0.49) | AMY1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |