Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28416781 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP2A6CLK1CLK2 | |
| SCHEMBL16698152 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TSHRCLK1CLK2CLK3 | |
| SCHEMBL24215830 | 0.78 | ALDH1A1 (0.48) | ALDH1A1TSHRCYP2A6CLK1CLK2 | |
| SCHEMBL9795798 | 0.78 | ALDH1A1 (0.38) | ALDH1A1TSHRCYP2A6CLK1CLK2 | |
| SCHEMBL27088321 | 0.76 | ALDH1A1 (0.33) | ALDH1A1TSHRCLK1CLK2CLK3 | |
| SCHEMBL28415836 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRCLK1CLK2CLK3 | |
| SCHEMBL31098032 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRCLK1CLK2CLK3 | |
| SCHEMBL22300296 | 0.74 | GRM5 (0.45) | ALDH1A1TSHRMAPT | |
| SCHEMBL16249165 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP2A6ALDH1A3KDM4E | |
| SCHEMBL29956523 | 0.74 | TSHR (0.43) | ALDH1A1TSHRCYP2A6ALDH1A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | KYOTO UNIVERSITY (JP) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | IGF2BP1, IGF2BP2, IGF2BP3 | ALDH1A1 2338/4885TSHR 3338/4885CYP2A6 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.