Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 3/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26375402 | 0.82 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1ALDH1A1KCNA3 | |
| SCHEMBL16709397 | 0.82 | NOTUM (0.39) | SLC1A3SLC1A2SLC1A1NFE2L2ALDH1A1 | |
| SCHEMBL16711687 | 0.82 | AKR1C3 (0.49) | ALDH1A1POLBL3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL17969145 | 0.82 | AKR1C3 (0.41) | SLC1A3SLC1A2SLC1A1NFE2L2ALDH1A1 | |
| SCHEMBL26704142 | 0.81 | SLC1A3 (0.45) | SLC1A3SLC1A2SLC1A1NFE2L2ALDH1A1 | |
| SCHEMBL30679636 | 0.81 | AKR1C3 (0.53) | NFE2L2ALDH1A1POLBL3MBTL1AKR1C3 | |
| SCHEMBL18002413 | 0.80 | HTR1A (0.40) | SLC1A3SLC1A2SLC1A1NFE2L2ALDH1A1 | |
| SCHEMBL16709388 | 0.80 | S1PR4 (0.41) | ALDH1A1KCNA3AKR1C3AKR1C2BRD4 | |
| SCHEMBL12629284 | 0.80 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1NFE2L2KCNA3 | |
| SCHEMBL30679637 | 0.79 | RORB (0.49) | NFE2L2ALDH1A1POLBL3MBTL1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | KYOTO UNIVERSITY (JP) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133467-A1 | SCREENING METHOD, PROTEIN INSTABILITY AND/OR STABILITY INDUCERS, AND PROTEIN ACTIVITY ASSESSMENT | IGF2BP1, IGF2BP2, IGF2BP3 | SLC1A3 3888/4885SLC1A2 3248/4885SLC1A1 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.